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癌症患者丧亲家属自杀意念相关因素:来自日本全国丧亲调查的结果。

Factors related to suicidal ideation among bereaved family members of patients with cancer: Results from a nationwide bereavement survey in Japan.

机构信息

Department of Palliative Nursing, Health Sciences, Tohoku University Graduate School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi 980-8575, Japan.

Department of Palliative and Supportive Care, Palliative Care Team, Seirei Mikatahara General Hospital, 3453 Mikatahara-cho, Kita-ku, Hamamatsu, Shizuoka 433-8558, Japan.

出版信息

J Affect Disord. 2022 Nov 1;316:91-98. doi: 10.1016/j.jad.2022.08.019. Epub 2022 Aug 12.

Abstract

BACKGROUND

Bereaved family members are known to have a higher risk of suicide, although relevant research is lacking. We aimed to clarify the percentage of bereaved family members of patients with cancer who experience suicidal ideation and the associated factors.

METHODS

We conducted a secondary analysis of two cross-sectional nationwide bereavement surveys in Japan, analyzing data from a total of 17,237 bereaved family members of patients with cancer. The Patient Health Questionnaire 8 (PHQ-8) and Item 9 of the PHQ-9 were used to assess depression (PHQ-8 score ≥10) and suicidal ideation, respectively. We assessed items such as socio-demographic data, complicated grief (CG), preparedness for bereavement, and perceived social support. Logistic regression analysis was used to reveal factors related to suicidal ideation.

RESULTS

Overall, 11 % of subjects reported some amount of suicidal ideation in the previous two weeks, with a suicidal ideation rate as high as 42 % among those with a higher risk of depression. Significant associations (all p < 0.0001) were found between suicidal ideation and the family member's depressive state (OR: 10.01), poor physical health status during caregiving (OR: 1.24), poor psychological health status during caregiving (OR: 1.38) pre-existing mental illness (OR: 1.38), insufficient preparedness for bereavement (OR: 0.59), and poor perceived social support (OR: 1.42).

LIMITATIONS

The respondents were limited to family members of patients with cancer in Japan, and the study involved cross-sectional self-reported data.

CONCLUSIONS

Clinicians should identify bereaved family members at a high risk of suicide by carefully assessing these risk factors identified in the present study.

摘要

背景

已知丧亲家庭成员自杀风险较高,但相关研究较少。本研究旨在明确癌症患者丧亲家庭成员出现自杀意念的比例及其相关因素。

方法

我们对日本两项全国性丧亲调查的二级分析数据进行了分析,共纳入 17237 名癌症患者丧亲家庭成员。使用患者健康问卷 8 项(PHQ-8)和 PHQ-9 项第 9 项评估抑郁(PHQ-8 得分≥10)和自杀意念。评估了社会人口学数据、复杂性悲伤(CG)、丧亲准备和感知社会支持等项目。使用逻辑回归分析揭示与自杀意念相关的因素。

结果

总体而言,11%的研究对象在过去两周内报告有过自杀意念,其中抑郁风险较高的患者自杀意念率高达 42%。自杀意念与家庭成员的抑郁状态(OR:10.01)、照顾期间身体健康状况差(OR:1.24)、照顾期间心理健康状况差(OR:1.38)、预先存在的精神疾病(OR:1.38)、对丧亲准备不足(OR:0.59)和感知社会支持差(OR:1.42)显著相关(均 P<0.0001)。

局限性

本研究的应答者仅限于日本癌症患者的家庭成员,且研究涉及横断面的自我报告数据。

结论

临床医生应通过仔细评估本研究确定的这些风险因素,识别自杀风险较高的丧亲家庭成员。

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