痴呆症中的地塞米松抑制试验。

The dexamethasone suppression test in dementia.

作者信息

Magni G, Schifano F, De Leo D, Zangaglia O

出版信息

Ital J Neurol Sci. 1987 Apr;8(2):125-8. doi: 10.1007/BF02337585.

Abstract

The dexamethasone suppression test (DST) was performed on 13 patients with multi-infarct dementia (MID), 5 patients with primary degenerative dementia (PDD) and 18 elderly controls. Abnormal lack of suppression was found in 7 demented patients (3 with PDD, 1 mild and 2 severe, and 4 with MID, 1 mild and 3 severe), and in 2 of the controls. Only one demented patient was depressed. The value of DST in the differential diagnosis of dementia from the major depressive disorders is discussed.

摘要

对13例多发梗死性痴呆（MID）患者、5例原发性退行性痴呆（PDD）患者和18名老年对照者进行了地塞米松抑制试验（DST）。在7例痴呆患者（3例PDD患者，1例轻度和2例重度；4例MID患者，1例轻度和3例重度）以及2名对照者中发现了异常的抑制缺乏。只有1例痴呆患者患有抑郁症。讨论了DST在痴呆与重度抑郁症鉴别诊断中的价值。