Ring J, Braun-Falco O
Hautarzt. 1987 Apr;38(4):198-205.
Apart from patient history, skin tests and in vitro methods, certain in vivo techniques such as elimination or provocation tests are of great importance in the diagnosis of food allergy. A variety of dietary approaches are used: elimination diets allow the evaluation of clinical improvement after the stepwise removal of suspected foods; on the other hand, provocation diets involve introducing suspected allergenic foods under clinical control. In each individual patient, a specific selection of food provocations is desirable. Food additives are tested according to the schedule of the oral provocation test for idiosyncrasy (OPTI) by the administration of increasing doses in gelatine capsules. In order to rule out psychological influences, blind techniques should be used. For longer periods, three variably intense allergy diets are recommended: Allergy diet 1 ("allergen-free" diet) is used in patients with severe clinical symptoms over a period of up to 2 weeks. Allergy diet 2 (allergen-poor diet) consists of a positively defined mixture of few permitted foods empirically rated as being weak allergens; this diet is suitable as a baseline diet over longer periods of time in patients with marked hypersensitivity reactions. Allergy diet 3 (additive-free diet) distinguishes permitted and prohibited foods. This diet is recommended for patients with pseudo-allergic reactions to additives such as colouring, preservatives or other triggers of pseudo-allergic reactions. In all dietary procedures, the problem of compliance has to be considered, not only with respect to the patient but also with regard to the medical personnel.(ABSTRACT TRUNCATED AT 250 WORDS)
除患者病史、皮肤试验和体外检测方法外,某些体内技术,如排除或激发试验,在食物过敏诊断中非常重要。人们采用了多种饮食方法:排除饮食可在逐步去除可疑食物后评估临床症状的改善情况;另一方面,激发饮食则是在临床监测下引入可疑的致敏食物。对于每个患者,都需要针对性地选择食物激发试验。食品添加剂按照特应性口服激发试验(OPTI)的方案进行检测,即通过在明胶胶囊中递增剂量给药。为排除心理影响,应采用盲法技术。在较长时间段内,推荐三种强度可变的过敏饮食:过敏饮食1(“无过敏原”饮食)用于临床症状严重的患者,为期可达2周。过敏饮食2(低过敏原饮食)由少量经经验判定为弱过敏原的允许食用食物组成的明确混合物;这种饮食适合在过敏反应明显的患者中长期作为基础饮食。过敏饮食3(无添加剂饮食)区分允许和禁止食用的食物。这种饮食推荐给对添加剂(如色素、防腐剂或其他引发假过敏反应的物质)有假过敏反应的患者。在所有饮食程序中,不仅要考虑患者的依从性问题,还要考虑医务人员的依从性问题。(摘要截断于250字)