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VDJdb in the pandemic era: a compendium of T cell receptors specific for SARS-CoV-2.

作者信息

Goncharov Mikhail, Bagaev Dmitry, Shcherbinin Dmitrii, Zvyagin Ivan, Bolotin Dmitry, Thomas Paul G, Minervina Anastasia A, Pogorelyy Mikhail V, Ladell Kristin, McLaren James E, Price David A, Nguyen Thi H O, Rowntree Louise C, Clemens E Bridie, Kedzierska Katherine, Dolton Garry, Rius Cristina Rafael, Sewell Andrew, Samir Jerome, Luciani Fabio, Zornikova Ksenia V, Khmelevskaya Alexandra A, Sheetikov Saveliy A, Efimov Grigory A, Chudakov Dmitry, Shugay Mikhail

机构信息

Institute of Bioorganic Chemistry of Russian Academy of Sciences, Moscow, Russia.

Center of Life Sciences, Skolkovo Institute of Science and Technology, Moscow, Russia.

出版信息

Nat Methods. 2022 Sep;19(9):1017-1019. doi: 10.1038/s41592-022-01578-0.

DOI:10.1038/s41592-022-01578-0
PMID:35970936
Abstract
摘要

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SARS-CoV-2-specific CD8 T-cell responses and TCR signatures in the context of a prominent HLA-A*24:02 allomorph.在主要 HLA-A*24:02 同种异型的背景下，SARS-CoV-2 特异性 CD8 T 细胞反应和 TCR 特征。
Immunol Cell Biol. 2021 Oct;99(9):990-1000. doi: 10.1111/imcb.12482. Epub 2021 Jun 30.
一个用于在单细胞分辨率下对转移性胰腺癌进行多部位免疫分析的平台。
Cancer Immunol Immunother. 2025 Aug 23;74(9):291. doi: 10.1007/s00262-025-04146-5.
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Predicting antigen-specific T-cell immunity against Wilms tumor 1 in hematologic cancer.预测血液系统癌症中针对威尔姆斯瘤1的抗原特异性T细胞免疫。
Leukemia. 2025 Aug 22. doi: 10.1038/s41375-025-02727-y.
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Predicting TCR-epitope recognition: How good are we?预测T细胞受体-表位识别：我们的水平如何？
Cell Genom. 2025 Aug 13;5(8):100975. doi: 10.1016/j.xgen.2025.100975.
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Breast cancer is detectable from peripheral blood using machine learning over T cell receptor repertoires.利用机器学习分析T细胞受体库，可从外周血中检测出乳腺癌。
NPJ Syst Biol Appl. 2025 Aug 8;11(1):89. doi: 10.1038/s41540-025-00573-3.
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bioRxiv. 2025 Jul 27:2025.07.23.666355. doi: 10.1101/2025.07.23.666355.
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