Mendenhall W M, Parsons J T, Mendenhall N P, Million R R
Int J Radiat Oncol Biol Phys. 1987 Jul;13(7):975-81. doi: 10.1016/0360-3016(87)90034-4.
This is an analysis of 99 patients with 100 T2-T4 previously untreated (56) or recurrent (44) carcinomas of the skin of the head and neck that were treated with radical irradiation between October 1964 and December 1983. Fifty-five patients had squamous cell carcinomas, 42 had basal cell carcinomas, and 3 had basosquamous carcinomas. The lesions were staged according to the AJCC staging system. All patients were observed for at least 2 years, and 71% had at least a 5-year follow-up. Eighty-four percent of recurrences were noted within 2 years of radiation therapy, and 97% within 5 years of treatment. This paper will present data on the initial and ultimate rates of local control, factors, such as bone, cartilage, and nerve invasion, that affect the likelihood of local control, determinate survival rates, and the incidence of treatment complications.
这是对99例患者的分析,这些患者有100处头颈部皮肤癌,之前未接受过治疗(56例)或复发(44例),于1964年10月至1983年12月期间接受了根治性放疗。55例患者患有鳞状细胞癌,42例患有基底细胞癌,3例患有基底鳞状细胞癌。病变根据美国癌症联合委员会(AJCC)分期系统进行分期。所有患者均观察至少2年,71%的患者至少有5年随访。84%的复发在放疗后2年内被发现,97%在治疗后5年内被发现。本文将呈现关于局部控制的初始和最终率、影响局部控制可能性的因素(如骨骼、软骨和神经侵犯)、确定生存率以及治疗并发症发生率的数据。