Milne Richard, Patch Christine
Engagement and Society, Wellcome Connecting Science, Hinxton, UK.
Kavli Centre for Ethics, Science and the Public, University of Cambridge, Cambridge, UK.
New Bioeth. 2023 Mar;29(1):24-36. doi: 10.1080/20502877.2022.2109697. Epub 2022 Aug 16.
The Covid-19 pandemic has demonstrated the potential of genomic technologies for the detection and surveillance of infectious diseases. Pathogen genomics is likely to play a major role in the future of research and clinical implementation of genomic technologies. However, unlike human genetics, the specific ethical and social challenges associated with the implementation of infectious disease genomics has received comparatively little attention. In this paper, we contribute to this literature, focusing on the potential consequences for individuals and communities of the use of these technologies. We concentrate on areas of challenges related to privacy, stigma, discrimination and the return of results in the cases of the surveillance of known pathogens, metagenomics and host genomics.
新冠疫情展现了基因组技术在传染病检测和监测方面的潜力。病原体基因组学很可能在基因组技术的未来研究和临床应用中发挥重要作用。然而,与人类遗传学不同,传染病基因组学应用所涉及的特定伦理和社会挑战受到的关注相对较少。在本文中,我们为这一领域的文献做出贡献,聚焦于这些技术应用对个人和社区可能产生的影响。我们重点关注在已知病原体监测、宏基因组学和宿主基因组学案例中与隐私、污名化、歧视及结果反馈相关的挑战领域。