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PHA4GE 微生物数据共享协议:建立基本共识的微生物数据共享规范,以促进跨部门合作。

The PHA4GE Microbial Data-Sharing Accord: establishing baseline consensus microbial data-sharing norms to facilitate cross-sectoral collaboration.

机构信息

Simon Fraser University Faculty of Health Sciences, Burnaby, Ottawa, Canada.

South African Medical Research Council Bioinformatics Unit, South African National Bioinformatics Institute, University of the Western Cape, Bellville, South Africa.

出版信息

BMJ Glob Health. 2024 Oct 30;9(10):e016474. doi: 10.1136/bmjgh-2024-016474.

Abstract

Microbial data sharing underlies evidence-based microbial research, as well as pathogen surveillance and analysis essential to public health. While the need for data sharing was highlighted during the SARS-CoV-2 pandemic, some concerns regarding secondary data use have also surfaced. Although general guidelines are available for data sharing, we note the absence of a set of established, universal, unambiguous and accessible principles to guide the secondary use of microbial data. Here, we propose the Public Health Alliance for Genomic Epidemiology (PHA4GE) Microbial Data-Sharing Accord to consolidate consensus norms and accepted practices for the secondary use of microbial data. The Accord provides a set of seven simple, baseline principles to address key concerns that may arise for researchers providing microbial datasets for secondary use and to guide responsible use by data users. By providing clear rules for secondary use of microbial data, the Accord can increase confidence in sharing by data providers and protect against data mis-use during secondary analyses.

摘要

微生物数据共享是循证微生物研究的基础,也是病原体监测和分析的基础,对公共卫生至关重要。虽然在 SARS-CoV-2 大流行期间强调了数据共享的必要性,但也出现了一些对二次数据使用的担忧。尽管有一般的数据共享指南,但我们注意到缺乏一套既定的、普遍的、明确的和易于获取的原则来指导微生物数据的二次使用。在这里,我们提出公共卫生基因组流行病学联盟(PHA4GE)微生物数据共享协议,以整合微生物数据二次使用的共识规范和公认做法。该协议提供了一套七个简单的基线原则,以解决为二次使用提供微生物数据集的研究人员可能出现的关键问题,并指导数据使用者负责任地使用数据。通过为微生物数据的二次使用提供明确的规则,该协议可以提高数据提供者共享数据的信心,并防止在二次分析过程中数据被滥用。

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