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A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infections-authors' response.

作者信息

Zhao Xu, Huang Haihui, Yuan Hong, Yuan Zhengyu, Zhang Yingyuan

机构信息

Institute of Antibiotics, Huashan Hospital, Fudan University, Shanghai, China.

Key Laboratory of Clinical Pharmacology of Antibiotics, National Health and Family Planning Commission, Shanghai, China.

出版信息

J Antimicrob Chemother. 2022 Oct 28;77(11):3210-3211. doi: 10.1093/jac/dkac282.

DOI:10.1093/jac/dkac282
PMID:35972415
Abstract
摘要

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1
A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infections-authors' response.一项评估口服康替唑胺与利奈唑胺治疗成人复杂性皮肤和软组织感染的疗效及安全性的Ⅲ期多中心、随机、双盲试验——作者回复
J Antimicrob Chemother. 2022 Oct 28;77(11):3210-3211. doi: 10.1093/jac/dkac282.
2
A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infections.一项评价口服康替唑与利奈唑胺治疗成人复杂性皮肤软组织感染的疗效和安全性的 III 期、多中心、随机、双盲临床试验。
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Comment on: A Phase III multicentre, randomized, double-blind trial to evaluate the efficacy and safety of oral contezolid versus linezolid in adults with complicated skin and soft tissue infections.评论：一项III期多中心、随机、双盲试验，旨在评估口服康替唑胺与利奈唑胺治疗成人复杂性皮肤和软组织感染的疗效及安全性。
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引用本文的文献

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Sequential Therapy of Linezolid and Contezolid to Treat Hematogenous Lung Abscess Caused by in a Congenital Cerebral Hypoplasia Patient: A Case Report.先天性脑发育不全患者血源性肺脓肿的利奈唑胺与克奈唑胺序贯治疗：一例报告
Infect Drug Resist. 2025 Jan 13;18:253-260. doi: 10.2147/IDR.S502839. eCollection 2025.
2
Plasma Concentrations of Contezolid and Its Efficacy and Safety in Elderly Patients with Multidrug-Resistant Tuberculosis and Renal Insufficiency.康替唑胺在耐多药结核病合并肾功能不全老年患者中的血药浓度及其疗效和安全性
Infect Drug Resist. 2024 Jul 15;17:3047-3056. doi: 10.2147/IDR.S468543. eCollection 2024.
3
Contezolid can replace linezolid in a novel combination with bedaquiline and pretomanid in a murine model of tuberculosis.
康奈唑胺可在新型联合方案中替代利奈唑胺，与贝达喹啉和德拉马尼联合用于结核分枝杆菌感染的小鼠模型。
Antimicrob Agents Chemother. 2023 Dec 14;67(12):e0078923. doi: 10.1128/aac.00789-23. Epub 2023 Nov 15.