National Center for PTSD, Boston VA Healthcare System, Boston, Massachusetts, USA.
Department of Psychiatry, Boston University School of Medicine, Boston, Massachusetts, USA.
J Clin Psychol. 2022 Nov;78(11):2214-2244. doi: 10.1002/jclp.23429. Epub 2022 Aug 16.
Posttraumatic stress disorder (PTSD) is associated with high comorbidity rates across the full range of psychiatric disorders. However, little is known about how psychiatric comorbidity manifests among people with PTSD, particularly with regard to concurrent diagnoses.
Latent class analysis (LCA) was used to characterize discrete classes of PTSD comorbidity using past year DSM-5 diagnostic standards among a large nationally representative epidemiologic sample of U.S. adults. Follow-up analyses compared participant characteristics across latent classes.
The LCA was best characterized by five classes: low comorbidity, distress-fear, distress-externalizing, mania-fear-externalizing, and mania-externalizing. Excluding the low comorbidity class, proportions of borderline and schizotypal personality disorder were high across classes.
Participant characteristics across classes of past year PTSD comorbidity are explored through the lens of case conceptualization and treatment planning utility.
创伤后应激障碍（PTSD）与各种精神障碍的高共病率有关。然而，对于 PTSD 患者中精神共病的表现形式，特别是同时存在的诊断，人们知之甚少。
使用潜伏类分析（LCA），根据美国成年人的大型全国代表性流行病学样本中过去一年的 DSM-5 诊断标准，对 PTSD 共病的离散类进行特征描述。后续分析比较了潜在类别中的参与者特征。
LCA 最好用五类来描述：低共病、苦恼-恐惧、苦恼-外化、躁狂-恐惧-外化和躁狂-外化。不包括低共病类别，在各类别中，边缘型和分裂型人格障碍的比例都很高。
通过案例概念化和治疗计划实用的角度探讨了过去一年 PTSD 共病各类别中参与者的特征。
