Yassa R, Nastase C, Camille Y, Henderson M, Belzile L, Beland F
J Clin Psychiatry. 1987 Jul;48(7):281-3.
Although carbamazepine is known to cause hyponatremia, no previous reports have indicated an interaction between carbamazepine and a diuretic. Two patients are described who were treated with this combination and developed symptomatic hyponatremia, which cleared when both drugs were discontinued in one patient and when the diuretic was discontinued in the second patient. The possible mechanisms of action of carbamazepine-induced hyponatremia are discussed.
虽然已知卡马西平会导致低钠血症，但此前并无报告表明卡马西平与利尿剂之间存在相互作用。本文描述了两名接受此联合治疗并出现症状性低钠血症的患者，其中一名患者停用两种药物后低钠血症症状消失，另一名患者停用利尿剂后症状消失。本文还讨论了卡马西平所致低钠血症可能的作用机制。
