Siriwardena Sanjula, McAllister Neil, Islam Salma, Craig John, Kinney Michael
School of Medicine, Queen's University Belfast, Belfast, UK.
Department of Neurology, Belfast Health and Social Care Trust, Belfast, UK.
Seizure. 2022 Oct;101:127-133. doi: 10.1016/j.seizure.2022.07.013. Epub 2022 Jul 28.
Sodium valproate is a significant human teratogen. Newspapers are a potential source of useful public health information, but the extent to which concerns around valproate were presented to the public via newspapers has not been evaluated.
To explore how sodium valproate has been portrayed by UK newspapers over the last several decades.
Thematic analysis of all newspaper articles up to July 2020 with key terms 'Valproate' and 'Epilim'. Articles were retrieved with LexisNexis. Temporal variation in thematic content was analysed.
275 articles were identified for analysis. Teratogenicity was the key theme in 86% of newspaper articles, failure of duty of care of medical professionals to communicate the risks of valproate in 68%, improving its regulation with public health interventions in 51% and litigation against Sanofi who produce valproate in 31%. Reporting was minimal pre-2000 and peaked in the recent 5 years.
Issues surrounding valproate have been covered by UK newspapers, with a predominant focus on its teratogenic effects.
丙戊酸钠是一种重要的人类致畸剂。报纸是有用的公共卫生信息的潜在来源,但围绕丙戊酸钠的担忧通过报纸向公众呈现的程度尚未得到评估。
探讨过去几十年英国报纸如何描述丙戊酸钠。
对截至2020年7月所有包含关键词“丙戊酸盐”和“丙戊酸”的报纸文章进行主题分析。文章通过LexisNexis检索。分析主题内容的时间变化。
共识别出275篇文章进行分析。致畸性是86%的报纸文章的关键主题,医疗专业人员未履行告知丙戊酸钠风险的注意义务占68%,通过公共卫生干预改善其监管占51%,对生产丙戊酸钠的赛诺菲进行诉讼占31%。2000年之前报道极少,最近5年达到峰值。
英国报纸报道了围绕丙戊酸钠的问题,主要关注其致畸作用。