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伊朗西南部食用植物油中多环芳烃的测定及基于蒙特卡洛模拟对消费者的潜在健康风险

Measurement of polycyclic aromatic hydrocarbons in edible oils and potential health risk to consumers using Monte Carlo simulation, southwest Iran.

作者信息

Barzegar Gelavizh, Rezaei Kalantary Roshanak, Bashiry Moein, Jaafarzadeh Nematollah, Ghanbari Farshid, Shakerinejad Ghodratollah, Khatebasreh Masoumeh, Sabaghan Mohamad

机构信息

Department of Environmental Health Engineering, Behbahan Faculty of Medical Sciences, Behbahan, Iran.

Research Center for Environmental Health Technology (RCEHT), Iran University of Medical Sciences, Tehran, Iran.

出版信息

Environ Sci Pollut Res Int. 2023 Jan;30(2):5126-5136. doi: 10.1007/s11356-022-22446-6. Epub 2022 Aug 17.

Abstract

Persistent organic pollutants, such as polycyclic aromatic hydrocarbons, are hazardous trace contaminants frequently observed in food ingredients, such as edible oils. This study aimed to measure PAHs in forty brands of edible oils marketed in southwest Iran. Additionally, we characterized the daily intake of MOE and ILCR using Monte Carlo simulation. To analyze the content of PAHs, the liquid-liquid extraction method followed by GC-MS was utilized. The average concentration of PAHs was mostly lower than the maximum value for individual PAH (2 μg/Kg); however, the average concentration of fluorene (3.86 μg/Kg) and benzo(a)anthracene (3.13 μg/Kg) was more than the permitted level. The highest residual concentrations of PAHs were mostly observed in canola and corn oils. The daily intake of BaP and 4-PAH for 95% of consumers was 0.01 ng/kg BW/day and 0.04 ng/kg BW/day, respectively. Also, MOE was more than 10,000 for the percentiles of 5%, 50%, and 95%. The modeled ILCR showed that consumption of oil does not currently pose a cancer risk for Iranian consumers due to PAHs exposure. Concerning potential health risks, consumption of edible oils is safe; however, regular monitoring and assessment are required.

摘要

持久性有机污染物,如多环芳烃,是在食用油等食品成分中经常观察到的有害微量污染物。本研究旨在测定伊朗西南部市场上销售的40个品牌食用油中的多环芳烃含量。此外,我们使用蒙特卡洛模拟法对MOE和ILCR的每日摄入量进行了表征。为了分析多环芳烃的含量,采用了液液萃取法,随后进行气相色谱 - 质谱分析。多环芳烃的平均浓度大多低于单个多环芳烃的最大值(2μg/Kg);然而,芴(3.86μg/Kg)和苯并(a)蒽(3.13μg/Kg)的平均浓度超过了允许水平。多环芳烃的最高残留浓度大多出现在菜籽油和玉米油中。95%的消费者对BaP和4 - PAH的每日摄入量分别为0.01 ng/kg体重/天和0.04 ng/kg体重/天。此外,对于5%、50%和95%的百分位数,MOE均大于10,000。模拟的ILCR表明,目前食用油消费因多环芳烃暴露不会对伊朗消费者构成癌症风险。关于潜在健康风险,食用油消费是安全的;然而,仍需要定期监测和评估。

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