伊朗食用植物油中的多环芳烃（PAHs）含量：一项风险评估研究。
Polycyclic aromatic hydrocarbons (PAHs) content of edible vegetable oils in Iran: A risk assessment study.
机构信息
Student Research Committee, Department of Food Sciences and Technology, National Nutrition and Food Technology Research Institute, Faculty of Nutrition Sciences and Food Technology Shahid Beheshti University of Medical Sciences, Tehran, Iran; Food Safety Research Center (Salt), School of Nutrition and Food Sciences, Semnan University of Medical Sciences, Semnan, Iran.
Department of Food Hygiene, Faculty of Veterinary Medicine, Semnan University, Semnan, Iran.
出版信息
Food Chem Toxicol. 2018 Aug;118:480-489. doi: 10.1016/j.fct.2018.05.063. Epub 2018 May 29.
Totally forty samples (23 brands) of different types of edible oils including frying oil (n = 14), blended oil (n = 13), sunflower oil (n = 6), corn oil (n = 5) and canola oil (n = 2) from Iran's market were analyzed for PAHs content by a High-performance liquid chromatography coupled with fluorescence detector. Also, the Health risk assessment in the adults and children consumers were estimated by the calculating margin of exposure (MOE) and the incremental lifetime cancer risk (ILCR) in the Monte Carlo Simulation (MCS) method. Approximately all of the samples contained different amounts of PAHs, while concentrations of BaP, PAH 4, PAH 8 and PAH 13 were reported as 0.90-11.33, 3.51-84.03, 7.41-117.12 and 129.28-19.54 μg/kg, respectively. Light polycyclic aromatic hydrocarbons corresponded to 65% of total PAHs while the remaining 35% belonged to heavy polycyclic aromatic hydrocarbons. Based on BaP content, 12 samples were above the standard limits (2 μg/kg) which set by the Standard Organization of Iran and the European Union, whereas 15 samples exceeded maximum limit 10 μg/kg set for PAH 4 established by EU. Percentile 95% of MOE in the adults due to ingestion of sunflower, corn, frying and blended oils were determined as 4.10E+5; 4.05E+5; , 2.17E+5, 2.33E+5, respectively and in the children due to ingestion of sunflower oil, corn oil, frying oil and blended oil were calculated as 5.38E+4, 4.49E+4, 2.86E+4, 3.37E+4. Regarding the percentile of 95% ILCR in the adults due to ingestion of sunflower oil, corn oil, frying oil and blended oil were reported as 4.5E-6, 4.17E-6l, 5.20E-6, 4.93E-6 and also this value in the children in the same rank order of products can be summarized as 3.43E-5, 3.94 E-5, 3.17E-5, 3.76E-5. The rank order of edible oils investigated based on MOE was sunflower oil > corn oil > blended oil > frying oil; and based on ILCR, frying oil > blended oil > sunflower oil > corn oil. The health risk assessment according to MCS method indicated that adults and children are not at considerable health risk; MOE ≥ 1E+4 and ILCR < 1E-4).
共分析了来自伊朗市场的 40 个不同类型的食用油脂样本（23 个品牌），包括煎炸油（n=14）、调和油（n=13）、葵花籽油（n=6）、玉米油（n=5）和菜籽油（n=2），以检测多环芳烃（PAHs）的含量。采用高效液相色谱-荧光检测器法对 40 个样本进行分析。此外，还采用蒙特卡罗模拟（MCS）法中的计算暴露边际（MOE）和增量终身癌症风险（ILCR）来评估成人和儿童消费者的健康风险。大约所有的样本都含有不同量的多环芳烃，而 BaP、PAH4、PAH8 和 PAH13 的浓度分别为 0.90-11.33、3.51-84.03、7.41-117.12 和 129.28-19.54μg/kg。低环多环芳烃占总多环芳烃的 65%，而其余 35%属于重多环芳烃。根据 BaP 含量，有 12 个样本超过了伊朗标准组织和欧盟设定的 2μg/kg 标准限值，另有 15 个样本超过了欧盟设定的 10μg/kg 对 PAH4 的最高限值。成人因食用葵花籽油、玉米油、煎炸油和调和油导致的 MOE 第 95 百分位数分别为 4.10E+5；4.05E+5；3.23E+5；2.33E+5。儿童因食用葵花籽油、玉米油、煎炸油和调和油导致的 MOE 第 95 百分位数分别为 5.38E+4；4.49E+4；2.86E+4；3.37E+4。关于成人因食用葵花籽油、玉米油、煎炸油和调和油导致的 ILCR 第 95 百分位数分别为 4.5E-6；4.17E-6；5.20E-6；4.93E-6；儿童因食用同一等级产品导致的 ILCR 第 95 百分位数分别为 3.43E-5；3.94E-5；3.17E-5；3.76E-5。根据 MOE 进行的食用油脂排名为葵花籽油>玉米油>调和油>煎炸油；根据 ILCR，排名为煎炸油>调和油>葵花籽油>玉米油。根据 MCS 方法进行的健康风险评估表明，成人和儿童不存在显著健康风险（MOE≥1E+4，ILCR<1E-4）。
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