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刚果民主共和国东部妊娠期糖尿病的流行情况。

Prevalence of gestational diabetes in Eastern Democratic Republic of Congo.

机构信息

Department of Obstetrics & Gynecology, La Sapientia Catholic University (UCS)/Goma, Goma, Congo.

Department of Internal Medicine, University of Goma (UNIGOM), Goma, Congo.

出版信息

BMC Pregnancy Childbirth. 2022 Aug 16;22(1):645. doi: 10.1186/s12884-022-04970-y.

DOI:10.1186/s12884-022-04970-y
PMID:35974333
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9380361/
Abstract

OBJECTIVE

To determine the prevalence of gestational diabetes and associated risk factors in the eastern region of the Democratic Republic of Congo (DRC).

METHODS

A cross-sectional study was conducted in Goma city, Idjwi, Ngungu and Rutshuru districts between April 2019 and February 2021. Pregnant women between 24-28 weeks of amenorrhea who consented to participate in the study were included. Blood sugar, anthropometric parameters and obstetrical and family history were studied. Gestational diabetes was defined as blood glucose level between 92 and 125 mg/dL.

RESULTS

The overall prevalence was 21.2% (n = 391) and was higher in Rutshuru [27.2% (n = 92)] and Goma [26.9% (n = 134)] compared to Ngungu [10.0% (n = 110)] (p = 0.005). An increased risk was associated with a history of a newborn weighing ≥ 4000 g [OR 2.4 95% CI (1.3 - 4.4)] or family diabetes [OR 2.9 95% CI (2.0 - 4.9)]. Median age in the pathological group was not different from that with normal blood glucose [25.0 (16.0 - 44.0) Vs 26.0 (16.0 - 44.0)] (p = 0.67). The prevalence tended to increase for pregnant women with a mid-upper arm circumference ≥ 280 mm [28.1% (n = 57)] Vs [19.3% (n = 322)] if < 280 mm, [OR (95% CI)] [1.5 (0.9-2.3)] (p = 0.13).

CONCLUSION

Gestational diabetes was found in one out of five pregnant women regardless their age. A history of macrosomia birth and diabetes in the family were the main risk factors.

摘要

目的

确定刚果民主共和国(DRC)东部地区妊娠期糖尿病的流行情况及其相关危险因素。

方法

本横断面研究于 2019 年 4 月至 2021 年 2 月在戈马市、伊吉维和恩冈古鲁以及鲁丘鲁区进行。纳入愿意参加研究的 24-28 周闭经的孕妇。研究了血糖、人体测量参数以及产科和家族史。妊娠期糖尿病定义为血糖水平在 92 至 125mg/dL 之间。

结果

总患病率为 21.2%(n=391),鲁丘鲁区[27.2%(n=92)]和戈马市[26.9%(n=134)]高于恩冈古鲁区[10.0%(n=110)](p=0.005)。有新生儿体重≥4000g[比值比(OR)2.4,95%置信区间(CI)1.3-4.4]或家族糖尿病[OR 2.9,95% CI(2.0-4.9)]病史的风险增加。在病理组中,中位年龄与血糖正常者无差异[25.0(16.0-44.0)VS 26.0(16.0-44.0)](p=0.67)。对于中上臂围≥280mm 的孕妇,其患病率趋于增加[28.1%(n=57)] VS [19.3%(n=322)]如果<280mm,[OR(95% CI)][1.5(0.9-2.3)](p=0.13)。

结论

无论年龄大小,每五个孕妇中就有一个患有妊娠期糖尿病。巨大儿分娩史和家族糖尿病史是主要危险因素。

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