Division of Urology, Department of Surgery, Nnamdi Azikiwe University, Awka, Nnewi Campus, Anambra State, Nigeria.
Niger J Clin Pract. 2022 Aug;25(8):1279-1286. doi: 10.4103/njcp.njcp_54_22.
Benign prostatic hypertrophy (BPH) is a common urological condition in men older than 50 years. It is important in the aetiologies of life-threatening obstructive uropathies. Ultrasound measurement of prostate volume is non-invasive, easily available, and a cost-effective method, useful in assessing bladder outlet obstruction (BOO). The International Prostate Symptoms Score (IPSS) on the other hand objectively assesses symptoms severity in BOO patients.
This study was aimed at determining the correlation between ultrasound-measured prostate volume and IPSS in men with BPH.
Following ethical approval from the Nnamdi Azikiwe University Teaching Hospital Ethical Committee, 100 patients who met the inclusion criteria and were diagnosed with clinical BPH were enrolled into the study. They had no other identifiable cause of BOO except BPH after clinical evaluation. The IPSS, Quality of life score (QOL), and prostate volumes were measured. Correlation between prostate volume, IPSS, and QOL were done using SPSS version 20. P value <0.05 was considered significant.
The mean age of patients was 69.3 ± 10.6 years with a range of 48-100 years. The mean prostate volume, IPSS, and QOL were 96.0 ± 70.5 cm, 15.63 ± 8.6, and 4.8 ± 1.3, respectively. The highest recorded IPSS was 35 and the lowest was 4, whereas the smallest and largest recorded prostate volumes were 19 cm and 350 cm, respectively. Nocturia was the major IPSS subscore. There was a weak positive correlation between prostate volume and IPSS in men with BPH (r = +0.109; P = 0.28) and between prostate volume and QOL (r = +0.072; P = 0.45). There was also a weak positive correlation between patients with only severe symptoms and corresponding prostate volumes (r = +0.122; P = 0.125). The correlation between patients with severe symptoms and their corresponding QOL was strong (r = +0.537; P = 0.135, respectively). These findings were, however, not statistically significant.
There is a weak positive correlation between prostate volume measured by ultrasound and symptoms severity scores in patients with BPH, although not statistically significant. This may be as a result of the small sample size. A larger sample size may be able to achieve statistical significance.
良性前列腺增生（BPH）是 50 岁以上男性常见的泌尿系统疾病。它在危及生命的梗阻性尿路疾病的病因中很重要。前列腺体积的超声测量是非侵入性的，易于获得，并且是一种具有成本效益的方法，可用于评估膀胱出口梗阻（BOO）。另一方面，国际前列腺症状评分（IPSS）客观评估 BOO 患者的症状严重程度。
本研究旨在确定 BPH 男性中超声测量的前列腺体积与 IPSS 之间的相关性。
在获得 Nnamdi Azikiwe 大学教学医院伦理委员会的伦理批准后，将符合纳入标准并被诊断为临床 BPH 的 100 名患者纳入研究。在临床评估后，除 BPH 外，他们没有其他可识别的 BOO 原因。测量了 IPSS、生活质量评分（QOL）和前列腺体积。使用 SPSS 版本 20 进行前列腺体积、IPSS 和 QOL 之间的相关性。P 值<0.05 被认为具有统计学意义。
患者的平均年龄为 69.3±10.6 岁，范围为 48-100 岁。平均前列腺体积、IPSS 和 QOL 分别为 96.0±70.5cm、15.63±8.6 和 4.8±1.3。记录的最高 IPSS 为 35，最低为 4，而记录的最小和最大前列腺体积分别为 19cm 和 350cm。夜尿症是主要的 IPSS 子评分。在患有 BPH 的男性中，前列腺体积与 IPSS 之间存在弱正相关（r=+0.109；P=0.28），前列腺体积与 QOL 之间也存在弱正相关（r=+0.072；P=0.45）。在只有严重症状的患者及其相应的前列腺体积之间也存在弱正相关（r=+0.122；P=0.125）。严重症状患者与其相应 QOL 之间的相关性较强（r=+0.537；P=0.135）。然而，这些发现没有统计学意义。
尽管没有统计学意义，但通过超声测量的前列腺体积与 BPH 患者的症状严重程度评分之间存在弱正相关。这可能是由于样本量小。更大的样本量可能能够达到统计学意义。
