Jimma Zone Health Office, Maternal and Child Health, Jimma, Ethiopia.
Department of population and family Health, Faculty Public Health, Institute of Health, 107839Jimma University, Jimma, Ethiopia.
J Int Assoc Provid AIDS Care. 2022 Jan-Dec;21:23259582221121096. doi: 10.1177/23259582221121096.
Drug adherence is the most significant in the progression of diseases. Thus, this study aimed to assess adherence and associated factors among seropositive people received treatment. Facility-based cross-sectional study was conducted in Jimma town public health facility from March to April 2019 on 385 selected participants. Systematic sampling technique was used to select study participants. The data were entered using Epi-data version 4.1 and analyzed by SPSS version 20 software. Variables with p-value of less than 0.25 in binary logistic regression were entered into the multivariable logistic regression to control cofounding A significance level of less than 0.05 was used in the final model to judge statistical significance. The magnitude of adherence to antiretroviral treatment was 69.4%. Food security (AOR = 1.75 (95% CI;(1.01-3.0), substance abuse (AOR = 0.55 (95% CI;(0.32-0.96), Didn't take other medications (AOR = 2.11(95%CI;(1.15-3.87), Good relationship with providers (AOR = 3.35(95%CI;(1.55-7.2), and irregular appointment (AOR = 0.19(95%CI; (0.11-0.34) were significantly associated. The magnitude of adherence to Anti-retroviral therapy was low compare to WHO. Food security, substance abuse, use of other medication, relationship with the health care providers, and irregular appointment were the factors associated. Treatment. Therefore, it is recommended that patients and health care workers enhance Antiretroviral Treatment adherence.
药物依从性是疾病进展中最重要的因素。因此,本研究旨在评估接受治疗的血清阳性患者的依从性及其相关因素。
本研究是 2019 年 3 月至 4 月在 Jimma 镇公共卫生机构进行的一项基于机构的横断面研究,共纳入了 385 名选定的参与者。采用系统抽样技术选择研究参与者。数据使用 EpiData 版本 4.1 输入,并使用 SPSS 版本 20 软件进行分析。二项逻辑回归中 p 值小于 0.25 的变量被纳入多变量逻辑回归中以控制混杂因素,最终模型中 p 值小于 0.05 的变量被认为具有统计学意义。
抗逆转录病毒治疗的依从性程度为 69.4%。粮食安全(AOR=1.75(95%CI;(1.01-3.0))、药物滥用(AOR=0.55(95%CI;(0.32-0.96))、未服用其他药物(AOR=2.11(95%CI;(1.15-3.87))、与提供者的良好关系(AOR=3.35(95%CI;(1.55-7.2))和不规则预约(AOR=0.19(95%CI;(0.11-0.34))与依从性显著相关。与世界卫生组织相比,抗逆转录病毒治疗的依从性程度较低。粮食安全、药物滥用、使用其他药物、与医疗保健提供者的关系和不规则预约是相关因素。因此,建议患者和医务人员提高抗逆转录病毒治疗的依从性。