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Effect of n-dipropylacetate on amino acid concentrations in mouse brain: correlations with anti-convulsant activity.

作者信息

Schechter P J, Tranier Y, Grove J

出版信息

J Neurochem. 1978 Nov;31(5):1325-7. doi: 10.1111/j.1471-4159.1978.tb06258.x.

DOI:10.1111/j.1471-4159.1978.tb06258.x
PMID:359762
Abstract
摘要

相似文献

1
Effect of n-dipropylacetate on amino acid concentrations in mouse brain: correlations with anti-convulsant activity.
J Neurochem. 1978 Nov;31(5):1325-7. doi: 10.1111/j.1471-4159.1978.tb06258.x.
2
Chronic valproic acid therapy and synaptic markers of amino acid neurotransmission.
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Central actions of valproic acid in man and in experimental models of epilepsy.
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Effects of chronic treatment with amino-oxyacetic acid or sodium n-dipropylacetate on brain GABA levels and the development and regression of cobalt epileptic foci in rats.用氨基氧乙酸或正丙基乙酸钠长期治疗对大鼠脑γ-氨基丁酸水平及钴致癫痫病灶的发生和消退的影响。
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Mechanism of anticonvulsant action of valproate.丙戊酸盐的抗惊厥作用机制。
Prog Neurobiol. 1982;19(4):315-59. doi: 10.1016/0301-0082(82)90010-7.
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Neurophysiological and biochemical changes evoked by valproic acid in the central nervous system.
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[Effects of sodium n-dipropylacetate on the GABA level in various areas of the mouse brain].[正丙基乙酸钠对小鼠脑不同区域γ-氨基丁酸水平的影响]
C R Seances Soc Biol Fil. 1976;170(6):1285-8.
9
Regional distribution in brain and effect on cerebral mitochondrial respiration of the anticonvulsive drug n-dipropylacetate.抗惊厥药物正丙基乙酸酯在脑内的区域分布及其对脑线粒体呼吸的影响。
Biochem Pharmacol. 1975 May 1;24(9):1055-8. doi: 10.1016/0006-2952(75)90447-5.
10
Anticonvulsant activity and effects of sodium dipropylacetate on cerebral 5-hydroxytryptamine and gamma-aminobutyric acid in reserpinized mice.丙戊酸钠对利血平化小鼠的抗惊厥活性及其对脑内5-羟色胺和γ-氨基丁酸的影响
Chem Pharm Bull (Tokyo). 1978 Nov;26(11):3551-5. doi: 10.1248/cpb.26.3551.

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Aspartate in the Brain: A Review.大脑中的天冬氨酸：综述
Neurochem Res. 2025 Jun 12;50(3):199. doi: 10.1007/s11064-025-04454-3.
2
Chronic administration of valproic acid induces a decrease in rat striatal glutamate and taurine levels.慢性给予丙戊酸可导致大鼠纹状体谷氨酸和牛磺酸水平降低。
Amino Acids. 1996 Jun;10(2):123-31. doi: 10.1007/BF00806585.
3
Comparison of the efficacy of two anticonvulsants, phenytoin and valproate to improve PCP and d-amphetamine induced deficits in a reversal learning task in the rat.两种抗惊厥药物苯妥英和丙戊酸盐改善大鼠逆向学习任务中苯环己哌啶和右旋苯丙胺诱导缺陷的疗效比较。
Front Behav Neurosci. 2009 Jun 11;3:8. doi: 10.3389/neuro.08.008.2009. eCollection 2009.
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Epilepsy and medication effects on the pattern visual evoked potential.癫痫及药物对图形视觉诱发电位的影响
Doc Ophthalmol. 2005 Jan;110(1):121-31. doi: 10.1007/s10633-005-7350-0.
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Basic pharmacology of valproate: a review after 35 years of clinical use for the treatment of epilepsy.丙戊酸盐的基础药理学：用于癫痫治疗35年临床应用后的综述
CNS Drugs. 2002;16(10):669-94. doi: 10.2165/00023210-200216100-00003.
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Antiepileptic drugs and mechanisms of epileptogenesis. A review.抗癫痫药物与癫痫发生机制。综述。
Ital J Neurol Sci. 1995 May;16(4):217-22. doi: 10.1007/BF02282992.
8
Behavioral studies using genetically defined mice: A bibliography (August 1978-July 1979).使用基因定义小鼠的行为学研究：一份文献目录（1978年8月 - 1979年7月）
Behav Genet. 1980 Jan;10(1):93-104. doi: 10.1007/BF01067321.
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Acute effects of sodium valproate and gamma-vinyl GABA on regional amino acid metabolism in the rat brain: incorporation of 2-[14C]glucose into amino acids.丙戊酸钠和γ-乙烯基γ-氨基丁酸对大鼠脑区氨基酸代谢的急性影响：2-[¹⁴C]葡萄糖掺入氨基酸的情况
Neurochem Res. 1982 Sep;7(9):1089-105. doi: 10.1007/BF00964888.
10
A comparative study of the pharmacology of inhibitors of GABA-metabolism.γ-氨基丁酸代谢抑制剂的药理学比较研究
Naunyn Schmiedebergs Arch Pharmacol. 1980;315(2):119-28. doi: 10.1007/BF00499254.