Department of Cardiology, Mersin City Training and Research Hospital, Mersin, Turkey.
Department of Emergency Medicine, Mehmet Akif Ersoy Canakkale State Hospital, Canakkale, Turkey.
Angiology. 2023 Aug;74(7):672-679. doi: 10.1177/00033197221113158. Epub 2022 Aug 17.
Prognostic nutritional index (PNI), consisting of inflammatory-nutritional parameters, has been investigated in terms of outcomes and renal function in patients with coronary artery disease. The objective of this study is to assess the predictive power of the PNI in predicting the risk for developing contrast-associated acute kidney injury (CA-AKI), an important complication following coronary angiography in patients with non-ST-elevation myocardial infarction (NSTEMI). The study population (336 patients with the diagnosis of NSTEMI) was divided into two groups: patients with CA-AKI and patients without CA-AKI. The mean age of the whole population was 62.0 ± 12.7 (21-95) years. CA-AKI was detected in 68 (20%) patients. Prognostic nutritional index values were significantly ( < .001) lower in the CA-AKI (+) group. Low PNI values (cutoff < 48.5%) were independent predictors of CA-AKI with Odds ratio (OR): .913, 95% confidence interval (CI): .866-.962, :.001, with a sensitivity 70.6% and specificity 69.4%. Prognostic nutritional index seems to be an easily assessable and promising scoring system that can be used in clinical practice for predicting the risk of developing CA-AKI.
预后营养指数(PNI)由炎症-营养参数组成,已在冠心病患者的预后和肾功能方面进行了研究。本研究旨在评估 PNI 在预测非 ST 段抬高型心肌梗死(NSTEMI)患者冠状动脉造影后发生对比剂相关急性肾损伤(CA-AKI)风险中的预测能力,CA-AKI 是一种重要的并发症。研究人群(336 例 NSTEMI 患者)分为两组:CA-AKI 患者和无 CA-AKI 患者。全人群的平均年龄为 62.0 ± 12.7(21-95)岁。68 例(20%)患者发生 CA-AKI。CA-AKI(+)组的预后营养指数值显著降低(<.001)。低 PNI 值(截断值<48.5%)是 CA-AKI 的独立预测因子,优势比(OR):.913,95%置信区间(CI):.866-.962,:.001,敏感性为 70.6%,特异性为 69.4%。预后营养指数似乎是一种易于评估和有前途的评分系统,可用于临床实践预测 CA-AKI 的发生风险。