Kim Jae Hyun, Yoon Jeong Hee, Bae Jae Seok, Park Sungeun, Han Seungchul, Lee Jeong Min
Department of Radiology, Konkuk University Medical Center, Konkuk University School of Medicine.
Department of Radiology and Center for Imaging Science, Samsung Medical Center, Sungkyunkwan University School of Medicine.
Invest Radiol. 2023 Feb 1;58(2):139-147. doi: 10.1097/RLI.0000000000000910. Epub 2022 Aug 15.
The aim of this study was to compare compressed sensing (CS) and view sharing (VS) techniques for single breath-hold multiarterial phase imaging with respect to image quality and focal liver observation detectability during gadoxetic acid-enhanced magnetic resonance imaging in patients at high risk for hepatocellular carcinoma (HCC).
A total of 385 patients who underwent gadoxetic acid-enhanced magnetic resonance imaging, including triple arterial phases using either CS (n = 224) or VS (n = 161) techniques, were retrospectively included. Among them, 117 patients had 171 focal liver observations (median diameter, 1.3 cm), which were classified according to Liver Imaging Reporting and Data System version 2018. The acquisition rate of optimally timed late arterial phase (LAP) was assessed, and image quality, including respiratory motion artifact and observation conspicuity, was rated on a 4-point scale by 3 radiologists. The Mann-Whitney U test and nonparametric test for repeated measures data were used for image quality and observation conspicuity analysis. The jackknife alternative free-response receiver operating characteristics method was used to compare the observation detectability between the 2 techniques.
The CS technique showed significantly higher acquisition rate of optimally timed LAP without transient severe motion (82.1% [184/224] vs 71.4% [115/161]; P = 0.013) than the VS technique. The CS technique also demonstrated significantly improved overall image quality (3.42 ± 0.70 vs 2.97 ± 0.61; P < 0.001) compared with the VS technique. Regarding the detection of hyperenhancing observations, there was no significant difference between the figure of merits of CS and VS techniques (0.660 vs 0.665; P = 0.890). However, the CS technique showed a higher detection rate in Liver Imaging Reporting and Data System M (LR-M, probably or definitely malignant but not HCC specific) observations than the VS technique (100.0% [9/9] vs 44.4% [8/18]; P = 0.009).
The CS technique tended to provide optimally timed LAP without transient severe motion and demonstrated greater detection rate of LR-M observations than the VS technique in patients at high risk of HCC.
本研究旨在比较压缩感知（CS）和视图共享（VS）技术在肝细胞癌（HCC）高危患者钆塞酸二钠增强磁共振成像中单次屏气多动脉期成像的图像质量和肝脏局灶性病变观察的可检测性。
回顾性纳入385例行钆塞酸二钠增强磁共振成像的患者，其中包括使用CS技术（n = 224）或VS技术（n = 161）进行的三期动脉期成像。其中117例患者有171个肝脏局灶性病变（中位直径1.3 cm），根据2018版肝脏影像报告和数据系统进行分类。评估最佳延迟动脉期（LAP）的采集率，3名放射科医生采用4分制对图像质量（包括呼吸运动伪影和病变清晰度）进行评分。采用Mann-Whitney U检验和重复测量数据的非参数检验进行图像质量和病变清晰度分析。采用留一法交替自由反应接收器操作特征法比较两种技术的病变可检测性。
CS技术显示最佳延迟LAP且无短暂严重运动的采集率显著高于VS技术（82.1% [184/224] 对71.4% [115/161]；P = 0.013）。与VS技术相比，CS技术的整体图像质量也显著提高（3.42 ± 0.70对2.97 ± 0.61；P < 0.001）。关于高增强病变的检测，CS和VS技术的优值之间无显著差异（0.660对0.665；P = 0.890）。然而，CS技术在肝脏影像报告和数据系统M（LR-M，可能或肯定为恶性但非HCC特异性）病变中的检测率高于VS技术（100.0% [9/9] 对44.4% [8/18]；P = 0.009）。
在HCC高危患者中，CS技术倾向于提供无短暂严重运动的最佳延迟LAP，且在LR-M病变的检测率方面高于VS技术。
