Department of Plant Physiology and Biochemistry, University of Hohenheim, 70593 Stuttgart, Germany.
Department of Plant Physiology and Biochemistry, University of Hohenheim, 70593 Stuttgart, Germany.
Curr Opin Plant Biol. 2022 Oct;69:102274. doi: 10.1016/j.pbi.2022.102274. Epub 2022 Aug 14.
Post-translationally modified peptides (PMPs) are important regulators of plant growth and development. They are derived from larger inactive precursors by post-translational modification (PTM) and proteolytic processing to result in the bioactive peptide signals. We discuss how and why these modifications contribute to the bioactivity of inflorescence deficient in abscission (IDA), phytosulfokine (PSK), and peptides of the Casparian strip integrity factor (CIF) family, as signaling molecules during reproductive development. The emerging picture suggests that PTMs evolved to increase the specificity of interaction of PMPs with cognate receptors and of PMP precursors with processing proteases. Cleavage sites in PMP precursors are recognized by subtilases (SBTs) in a highly specific manner. SBT-mediated processing results in the activation of PMP signals regulating stress-induced flower drop, the formation of the embryonic cuticle, and pollen development.
翻译后修饰肽 (PMPs) 是植物生长和发育的重要调节剂。它们由较大的无活性前体通过翻译后修饰 (PTM) 和蛋白水解加工而来，从而产生生物活性肽信号。我们讨论了这些修饰如何以及为何有助于脱落缺陷 (IDA)、植物磺肽 (PSK) 和 Casparian 带完整性因子 (CIF) 家族肽等生殖发育过程中作为信号分子的生物活性。新兴的图景表明，PTM 进化是为了增加 PMP 与同源受体以及 PMP 前体与加工蛋白酶相互作用的特异性。PMP 前体中的切割位点被枯草杆菌蛋白酶 (SBT) 以高度特异性的方式识别。SBT 介导的加工导致调节应激诱导的花脱落、胚胎角质层形成和花粉发育的 PMP 信号的激活。
