Klinik für diagnostische und interventionelle Radiologie und Neuroradiologie, Universitätsklinikum Augsburg, Germany.
Institut für Klinische Radiologie, Campus Grosshadern, Klinikum der Universität München, Munchen, Germany.
Rofo. 2022 Nov;194(11):1204-1215. doi: 10.1055/a-1826-0325. Epub 2022 Aug 17.
Ultrasound is one of the most important imaging methods in the daily routine. Contrast-enhanced ultrasound (CEUS) has put ultrasound on equal footing with computed tomography and magnetic resonance imaging in many areas. Although ultrasound contrast agents are commonly administered intravenously, endocavitary application as performed in the case of iodine-containing contrast agents is also possible.
Based on the current literature, this overview provides information regarding possible endocavitary applications of ultrasound contrast agents as they are used and could be used in the daily routine in radiology. Examples are provided to illustrate the advantages and disadvantages of clinical use.
Endocavitary CEUS broadens the spectrum of possible ultrasound applications and can be safely used for patient diagnosis and treatment. The method can be safely used for diagnosis and patient management, particularly in patients in whom examinations including exposure to radiation with iodine-containing contrast agents may be contraindicated and who have limited mobility due to disease severity.
· Endocavitary CEUS is a safe method that can be readily learned by those with prior ultrasound training. Radiologists benefit from their existing knowledge of contrast-enhanced imaging.. · With ultrasound contrast agents, endocavitary examinations comparable to CT and fluoroscopy can be performed without having to take radiation exposure, preexisting conditions, and patient mobility into consideration.. · In principle, endocavitary CEUS can access every body cavity (physiological and pathological) and body orifice with any access device.. · The method is mainly used for interventions including puncture and drainage. The diluted ultrasound contrast agent can be continuously visualized in the access device and in the target region, including distribution within the target region, with high spatial and temporal resolution. Voiding urosonography and visualization of the salivary duct system should also be mentioned in the radiological context.. · Poor B-mode imaging conditions typically also mean poor CEUS conditions. Imaging methods that can reliably evaluate low-lying structures and structures with overlying air, particularly in obese patients, without artifacts and can provide a good overview have a clear advantage here..
· Vollert K, Clevert DA, Kleffel T. Endocavitary Contrast-Enhanced Ultrasound. Fortschr Röntgenstr 2022; 194: 1204 - 1214.
超声是日常工作中最重要的影像学方法之一。与计算机断层扫描和磁共振成像相比，超声造影（CEUS）在许多领域已经达到了同等地位。尽管超声造影剂通常经静脉内给药，但也可以进行腔内应用，如含碘造影剂的腔内应用。
基于目前的文献，本文综述介绍了超声造影剂在放射学日常实践中可能的腔内应用，包括已应用和未来可能应用的领域。本文通过举例说明了临床应用的优缺点。
腔内 CEUS 拓宽了超声应用的范围，可安全用于患者诊断和治疗。该方法可安全用于诊断和患者管理，特别是在那些可能因含碘造影剂检查而受到辐射暴露禁忌、因疾病严重程度而活动受限的患者中。
·腔内 CEUS 是一种安全的方法，具有超声培训背景的人员可轻松掌握。放射科医生可利用其现有的对比增强成像知识获益。·使用超声造影剂，可以进行与 CT 和透视检查相媲美的腔内检查，而无需考虑辐射暴露、基础疾病和患者的活动度。·原则上，腔内 CEUS 可以进入所有体腔（生理性和病理性）和体腔开口，并使用任何进入装置。·该方法主要用于包括穿刺和引流在内的介入治疗。稀释后的超声造影剂可以在进入装置和目标区域中连续可视化，包括在目标区域内的分布情况，具有较高的空间和时间分辨率。还应提到放射学背景下的排遗超声检查和唾液腺系统可视化。·较差的 B 型超声成像条件通常也意味着较差的 CEUS 条件。对于那些能够可靠评估低位结构和有上方气体覆盖的结构的成像方法，尤其是在肥胖患者中，无伪影且能提供良好的整体评估，具有明显的优势。
·Vollert K, Clevert DA, Kleffel T. 腔内对比增强超声。国际医学放射学杂志 2022; 94: 1204-1214.
