Division of Psychiatry and Applied Psychology, School of Medicine, University of Nottingham, Nottingham, UK.
Division of Psychiatry and Applied Psychology, School of Medicine, University of Lincoln, Lincoln, UK.
Eur J Cancer Care (Engl). 2022 Nov;31(6):e13678. doi: 10.1111/ecc.13678. Epub 2022 Aug 17.
The present review aimed to establish prevalence rates of anxiety and depression in adults with haematology cancer, with a focus on the differences between patients under treatment and patients under watchful waiting.
Five databases (Scopus, Medline, PsycINFO, EThOS, CINAHL) were searched throughout June 2021. Key search terms included haematology cancer, anxiety, depression, in treatment and watchful waiting. Study and sample characteristics, prevalence rates and mean self-reported scores of anxiety and depression data were extracted.
A total of 18 eligible papers were included in the review. Quality appraisal indicated papers were of adequate standard. Depression data from 2720 participants (14.5% under watchful waiting) and anxiety data from 2520 participants (15.9% under watchful waiting) were analysed through subgroup meta-analyses. The prevalence of anxiety was 34% amongst adults receiving treatment and 24.5% amongst those under watchful waiting. The prevalence of depression amongst adults receiving treatment was 31.3%, significantly higher than 16.1% of adults under watchful waiting.
Overall, adults with haematology cancer were at greater risk of experiencing anxiety and depression than the general population, with greatest risk in those under treatment. The findings indicate the need for future research to examine availability and effectiveness of targeted psychological interventions.
本综述旨在确定血液癌症成年患者中焦虑和抑郁的患病率，并重点关注治疗中和观察等待中的患者之间的差异。
2021 年 6 月期间，在五个数据库（Scopus、Medline、PsycINFO、EThOS、CINAHL）中进行了搜索。主要搜索词包括血液癌症、焦虑、抑郁、治疗中和观察等待。提取了研究和样本特征、焦虑和抑郁数据的患病率和平均自我报告评分。
综述共纳入 18 篇符合条件的论文。质量评估表明，这些论文的标准足够。通过亚组荟萃分析分析了来自 2720 名参与者（14.5%处于观察等待）的抑郁数据和来自 2520 名参与者（15.9%处于观察等待）的焦虑数据。接受治疗的成年人中焦虑的患病率为 34%，而处于观察等待的成年人中焦虑的患病率为 24.5%。接受治疗的成年人中抑郁的患病率为 31.3%，明显高于处于观察等待的成年人中抑郁的患病率 16.1%。
总体而言，血液癌症成年患者比一般人群更容易出现焦虑和抑郁，治疗中的患者风险最大。这些发现表明需要进一步研究，以检查有针对性的心理干预措施的可用性和有效性。
