TREMble Before TREM2: The Mighty Microglial Receptor Conferring Neuroprotective Properties in TDP-43 Mediated Neurodegeneration.
作者信息
Mills William A, Eyo Ukpong B
机构信息
Brain Immunology and Glia Center, University of Virginia, Charlottesville, VA, 22903, USA.
Department of Neuroscience, University of Virginia, Charlottesville, VA, 22903, USA.
出版信息
Neurosci Bull. 2023 Jan;39(1):163-166. doi: 10.1007/s12264-022-00944-4. Epub 2022 Aug 17.
Abstract
摘要
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Diverse human astrocyte and microglial transcriptional responses to Alzheimer's pathology.人类星形胶质细胞和小胶质细胞对阿尔茨海默病病理的转录反应具有多样性。
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Structural basis of the interplay between α-synuclein and Tau in regulating pathological amyloid aggregation.α-突触核蛋白与 Tau 相互作用调节病理性淀粉样聚集的结构基础。
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