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间歇运动对运动员心肌缺血再灌注损伤的保护作用。

The Protective Effect of Interval Exercise on Myocardial Ischemia-Reperfusion Injury in Players.

机构信息

School of Physical Education, Xi'an Physical Education University, Xi'an, 710065 Shaanxi, China.

出版信息

Biomed Res Int. 2022 Aug 8;2022:4353340. doi: 10.1155/2022/4353340. eCollection 2022.

Abstract

In recent years, the popularity of sports has been increasing. In the high-intensity competition, many players have been injured; most of them are myocardial ischemia. With the development of medical science and technology, myocardial ischemia can be reperfusion. However, sometimes, the function of tissues and organs cannot be restored, but the dysfunction and structural damage of tissues and organs can be aggravated. Therefore, it is necessary to actively carry out intermittent exercise to protect players from myocardial ischemia-reperfusion injury. The purpose of this paper is to explore the protective effect of intermittent exercise on the myocardial ischemia-reperfusion injury of players. 60 clean male Sprague Dawley (SD) old rats were selected as the research objects, which were divided into control group, ischemia/reperfusion model group, intermittent exercise + model group, and intermittent exercise + control group, and compared the parameters of heart function indexes of each group. The results showed that the creatine kinase (CK) content of control group was 0.577 ± 0.176 u/ml, lactate dehydrogenase (LDH) content was 7.834 ± 1.507 u/ml, model group was 1.257 ± 0.113 u/ml, lactate dehydrogenase (LDH) content was 14.441 ± 1.793 u/ml, intermittent exercise + model group was 0.987 ± 0.127 u/ml, lactate dehydrogenase (LDH) content was 11.714 ± 3.017 u/ml, intermittent exercise + control group was 1.103 ± 0.125 u/ml, and lactate dehydrogenase (LDH) content was 14.647 ± 2.575 u/ml. It can be seen that intermittent exercise has a good protective effect on myocardial ischemia-reperfusion injury. If the interval exercise method is integrated into the daily training of athletes, it can effectively improve the perfusion injury caused by myocardial ischemia.

摘要

近年来,体育运动的普及度不断提高。在高强度的竞争中,许多运动员都受伤了;其中大多数是心肌缺血。随着医疗科学技术的发展,心肌缺血可以再灌注。然而,有时组织和器官的功能无法恢复,但组织和器官的功能障碍和结构损伤会加剧。因此,有必要积极开展间歇性运动,以保护运动员免受心肌缺血再灌注损伤。本文旨在探讨间歇性运动对运动员心肌缺血再灌注损伤的保护作用。选取 60 只清洁雄性 Sprague Dawley(SD)大鼠作为研究对象,将其分为对照组、缺血/再灌注模型组、间歇运动+模型组和间歇运动+对照组,比较各组心功能指标参数。结果显示,对照组肌酸激酶(CK)含量为 0.577±0.176u/ml,乳酸脱氢酶(LDH)含量为 7.834±1.507u/ml,模型组 CK 含量为 1.257±0.113u/ml,LDH 含量为 14.441±1.793u/ml,间歇运动+模型组 CK 含量为 0.987±0.127u/ml,LDH 含量为 11.714±3.017u/ml,间歇运动+对照组 CK 含量为 1.103±0.125u/ml,LDH 含量为 14.647±2.575u/ml。可见,间歇性运动对心肌缺血再灌注损伤有较好的保护作用。如果将间歇运动方法融入运动员的日常训练中,可有效改善因心肌缺血引起的灌注损伤。

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