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成人右下第二前磨牙牙髓血运重建:一例报告

Pulp revascularization on an adult mandibular right second premolar: A case report.

作者信息

Yang Ye-Qing, Wu Bu-Ling, Zeng Jun-Kai, Jiang Chong, Chen Ming

机构信息

Department of Stomatology, Stomatological Hospital of Southern Medical University, Guangzhou 510280, Guangdong Province, China.

Shenzhen Stomatology Hospital (Pingshan), Southern Medical University, Shenzhen 518118, Guangdong Province, China.

出版信息

World J Clin Cases. 2022 Jun 16;10(17):5833-5840. doi: 10.12998/wjcc.v10.i17.5833.

DOI:10.12998/wjcc.v10.i17.5833
PMID:35979092
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9258393/
Abstract

BACKGROUND

Pulp revascularization has become a new method for the treatment of periapical diseases in young permanent teeth in recent years. Through root canal flushing and disinfection, avoiding mechanical preparation, guiding apical stem cells into the root canal and promoting the continuous development of tooth roots, it has achieved good clinical curative effects. But in adult patients with chronic periapical periodontitis with immature roots and open apices, apical barrier technology is often used to treat these teeth.

CASE SUMMARY

Pulp revascularization of a 26-year-old patient's tooth was performed using cefaclor instead of minocycline and iRoot BP instead of mineral trioxide aggregate as intracanal medication. The case was followed up for 36 mo. Observations showed evidence of regression of clinical signs and symptoms, resolution of apical periodontitis and no discolouration of affected teeth.

CONCLUSION

For adult patients with chronic periapical periodontitis with immature roots and open apices, pulp revascularisation showed favourable results in treating these teeth.

摘要

背景

近年来,牙髓血运重建已成为治疗年轻恒牙根尖周病的一种新方法。通过根管冲洗和消毒,避免机械预备,引导根尖干细胞进入根管并促进牙根的继续发育,已取得了良好的临床疗效。但对于牙根未发育成熟、根尖孔开放的成年慢性根尖周炎患者,常采用根尖屏障技术来治疗这些牙齿。

病例摘要

对一名26岁患者的牙齿进行牙髓血运重建,使用头孢克洛代替米诺环素,使用iRoot BP代替矿物三氧化物凝聚体作为根管内用药。对该病例进行了36个月的随访。观察结果显示临床体征和症状有消退迹象,根尖周炎得到解决,患牙未变色。

结论

对于牙根未发育成熟、根尖孔开放的成年慢性根尖周炎患者,牙髓血运重建在治疗这些牙齿方面显示出良好的效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3295/9258393/813d1106a957/WJCC-10-5833-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3295/9258393/3d0ae2224c19/WJCC-10-5833-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3295/9258393/ababf35831a2/WJCC-10-5833-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3295/9258393/1aa46d7c8242/WJCC-10-5833-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3295/9258393/813d1106a957/WJCC-10-5833-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3295/9258393/3d0ae2224c19/WJCC-10-5833-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3295/9258393/ababf35831a2/WJCC-10-5833-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3295/9258393/1aa46d7c8242/WJCC-10-5833-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3295/9258393/813d1106a957/WJCC-10-5833-g004.jpg

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本文引用的文献

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J Biol Regul Homeost Agents. 2020 Nov-Dec;34(6 Suppl. 3):1-10.
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A second attempt at pulp revascularisation on an immature traumatised anterior tooth: a case report with two-year follow-up.二次牙髓血运重建术治疗年轻外伤前牙:附两年随访的病例报告。
Aust Endod J. 2021 Apr;47(1):90-96. doi: 10.1111/aej.12466. Epub 2020 Nov 28.
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The Emerging Role of Stem Cells in Regenerative Dentistry.
干细胞在再生牙医学中的新兴作用。
Curr Gene Ther. 2020;20(4):259-268. doi: 10.2174/1566523220999200818115803.
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New Application of Osteogenic Differentiation from HiPS Stem Cells for Evaluating the Osteogenic Potential of Nanomaterials in Dentistry.人诱导多能干细胞成骨分化在牙科学中评估纳米材料成骨潜力的新应用。
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