do Couto Aline Maria, Espaladori Marcela Carvalho, Leite Anamaria Pessoa Pereira, Martins Carolina Castro, de Aguiar Maria Cássia Ferreira, Abreu Lucas Guimarães
Dr. do Couto, PhD candidate, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil;, Email:
Dr. Espaladori, PhD candidate, School of Dentistry, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil.
Pediatr Dent. 2019 Sep 15;41(5):341-353.
The purpose of this systematic review was to summarize the clinical and radiographic results of pulp revascularization procedures employing a triple antibiotic paste in teeth with incomplete root formation. Electronic searches were conducted in February 2017 using PubMed, Medline, Web of Science, Scopus, The Cochrane Library, ProQuest, Lilacs and The Brazilian Library of Dentistry, UK National Institute for Health and Care Excellence, U.S. National Institutes of Health, Clinical Trials, and Google. The search was updated in March 2019. Clinical trials in English, Portuguese, and Spanish, without any restrictions regarding the year of publication, were included. The quality of the studies was analyzed using the Cochrane Collaboration tool. The search retrieved 1,768 references, and eight studies were included for a qualitative analysis. In these eight studies, the risk of bias across the Cochrane tool's domains varied from low to unclear. The included studies demonstrated that the clinical and radiographic success of pulp revascularization using calcium hydroxide or triple antibiotic paste appears to resolve symptoms and periapical healing. Triple antibiotic paste is effective in the pulp revascularization therapy of teeth with incomplete root formation. Absence of symptoms and the achievement of periapical integrity have been observed. (Pediatr Dent 2019;41(5):341-53).
本系统评价的目的是总结在牙根发育不全的牙齿中采用三联抗生素糊剂进行牙髓血运重建术的临床和影像学结果。2017年2月，通过PubMed、Medline、Web of Science、Scopus、Cochrane图书馆、ProQuest、Lilacs和巴西牙科学图书馆、英国国家卫生与临床优化研究所、美国国立卫生研究院、临床试验以及谷歌进行了电子检索。2019年3月更新了检索。纳入了发表年份无限制的英文、葡萄牙文和西班牙文的临床试验。使用Cochrane协作工具分析研究质量。检索共获得1768篇参考文献，纳入8项研究进行定性分析。在这8项研究中，Cochrane工具各领域的偏倚风险从低到不明确不等。纳入的研究表明，使用氢氧化钙或三联抗生素糊剂进行牙髓血运重建的临床和影像学成功率似乎能缓解症状并实现根尖周愈合。三联抗生素糊剂在牙根发育不全牙齿的牙髓血运重建治疗中有效。已观察到无症状且根尖周完整性得以实现。（《儿科牙科学》2019年；41(5):341 - 53）
