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超声引导下微波消融术治疗蕈样肉芽肿累及眼睑的姑息治疗：一例报告

Ultrasound-guided microwave ablation as a palliative treatment for mycosis fungoides eyelid involvement: A case report.

作者信息

Chen Yan-Wei, Yang Hai-Zhen, Zhao Shuang-Shuang, Zhang Zheng, Chen Zhe-Ming, Feng Hua-Hui, An Mao-Hui, Wang Ke-Ke, Duan Ran, Chen Bao-Ding

机构信息

Department of Medical Ultrasound, The Affiliated Hospital of Jiangsu University, Zhenjiang 212000, Jiangsu Province, China.

出版信息

World J Clin Cases. 2022 Jun 16;10(17):5825-5832. doi: 10.12998/wjcc.v10.i17.5825.

DOI:10.12998/wjcc.v10.i17.5825
PMID:35979116
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9258385/
Abstract

BACKGROUND

Mycosis fungoides (MF) is a form of lymphoma derived from heterogeneous T cells, and eyelid involvement is extremely rare. The common methods to treat eyelid involvement are radiotherapy and chemotherapy, but their efficacies are limited. Herein, we report a case of advanced-stage MF eyelid involvement, propose ultrasound (US)-guided microwave ablation (MWA) therapy and present a literature review.

CASE SUMMARY

A male patient was admitted to our hospital in June 2018 and diagnosed with MF radiological and histopathological examinations. The patient's condition was not well controlled by various conventional chemotherapies. US-guided MWA was performed to relieve the patient's symptoms and improve his quality of life, showing satisfactory efficacy.

CONCLUSION

Eyelid involvement is one of the most troublesome clinical problems for advanced-stage MF patients. This is the first report on the use of US-guided MWA as a palliative therapy for MF eyelid involvement; the treatment successfully relieved the patient's clinical symptoms and reduced his anxiety behaviours. Our study sheds new light on methods for improving the clinical management of eyelid involvement in MF.

摘要

背景

蕈样肉芽肿（MF）是一种源自异质性T细胞的淋巴瘤形式，眼睑受累极为罕见。治疗眼睑受累的常用方法是放疗和化疗，但其疗效有限。在此，我们报告1例晚期MF眼睑受累病例，提出超声（US）引导下微波消融（MWA）治疗并进行文献复习。

病例摘要

1例男性患者于2018年6月入院，经放射学和组织病理学检查诊断为MF。该患者的病情未通过各种传统化疗得到有效控制。实施US引导下MWA以缓解患者症状并改善其生活质量，疗效令人满意。

结论

眼睑受累是晚期MF患者最棘手的临床问题之一。这是关于使用US引导下MWA作为MF眼睑受累姑息治疗的首例报告；该治疗成功缓解了患者的临床症状并减少了其焦虑行为。我们的研究为改善MF眼睑受累的临床管理方法提供了新线索。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e0/9258385/07ead89f5813/WJCC-10-5825-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e0/9258385/a2dd5cdf4e0b/WJCC-10-5825-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e0/9258385/220a0fe2c9c8/WJCC-10-5825-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e0/9258385/ae7616b9d352/WJCC-10-5825-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e0/9258385/d482c2600c87/WJCC-10-5825-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e0/9258385/07ead89f5813/WJCC-10-5825-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e0/9258385/a2dd5cdf4e0b/WJCC-10-5825-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e0/9258385/220a0fe2c9c8/WJCC-10-5825-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e0/9258385/ae7616b9d352/WJCC-10-5825-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e0/9258385/d482c2600c87/WJCC-10-5825-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f8e0/9258385/07ead89f5813/WJCC-10-5825-g005.jpg

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Mycosis Fungoides and Sézary Syndrome: Updates and Review of Current Therapy.蕈样肉芽肿和赛泽里综合征：当前治疗方法的更新和综述。
Curr Treat Options Oncol. 2021 Jan 7;22(2):10. doi: 10.1007/s11864-020-00809-w.
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Percutaneous Ablation-Induced Immunomodulation in Hepatocellular Carcinoma.经皮消融治疗诱导的肝细胞癌免疫调节。
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Palliative and End-of-Life Care for Patients With Hematologic Malignancies.血液系统恶性肿瘤患者的姑息治疗和终末期关怀。
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Severe upper eyelid mass in a patient with mycosis fungoides.蕈样肉芽肿患者的严重上眼睑肿块。
Orbit. 2020 Apr;39(2):150-152. doi: 10.1080/01676830.2019.1639772. Epub 2019 Jul 16.
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Mycosis Fungoides and Sézary Syndrome: An Update.蕈样肉芽肿和赛泽里综合征：最新进展。
Hematol Oncol Clin North Am. 2019 Feb;33(1):103-120. doi: 10.1016/j.hoc.2018.09.001.
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Microwave Ablation (MWA): Basics, Technique and Results in Primary and Metastatic Liver Neoplasms - Review Article.微波消融（MWA）：原发性和转移性肝脏肿瘤的基础、技术及结果——综述文章
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