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一名患者同时患有酒精性肝硬化和恶性腹膜间皮瘤:病例报告。

Concurrent alcoholic cirrhosis and malignant peritoneal mesothelioma in a patient: A case report.

作者信息

Liu Liang, Zhu Xiao-Yan, Zong Wen-Jie, Chu Chuan-Lian, Zhu Jing-Yu, Shen Xing-Jie

机构信息

Department of Gastroenterology, Central Hospital Affiliated to Shandong First Medical University, Jinan 250011, Shandong Province, China.

出版信息

World J Clin Cases. 2022 Jul 6;10(19):6716-6721. doi: 10.12998/wjcc.v10.i19.6716.

Abstract

BACKGROUND

Malignant peritoneal mesothelioma (MPM) originates from the mesothelial and subcutaneous cells of the abdominal cavity. Its diagnose is difficult due to its nonspecific and vague symptoms, and it should be differentiated from alcoholic cirrhosis and liver and pancreatic cancers. Misdiagnosis and missed diagnosis can easily occur when MPM presents with other diseases. To the best of our knowledge, no case of MPM concurrent with alcoholic cirrhosis has been reported.

CASE SUMMARY

A 63-year-old man presented to our hospital with abdominal distension for 20days. He had a history of alcohol consumption for nearly 30 years and no history of special drug use or toxic exposure. After treatment for alcoholic cirrhosis in a community hospital, his symptoms did not improve significantly. The patient underwent exploratory laparotomy and surgical resection. Pathologic examination showed an epithelioid MPM. He was treated with chemotherapy and intraperitoneal hyperthermic perfusion after surgery. Currently, he is in a stable condition and tumor recurrence has not occurred.

CONCLUSION

Misdiagnosis and missed diagnosis of MPM can easily occur because of its insidious onset. Therefore, there is a need to understand. MPM in clinical practice, make the correct diagnosis, and provide timely and effective treatment.

摘要

背景

恶性腹膜间皮瘤(MPM)起源于腹腔的间皮细胞和皮下细胞。由于其症状不具特异性且模糊,其诊断较为困难,并且应与酒精性肝硬化以及肝癌和胰腺癌相鉴别。当MPM合并其他疾病时,很容易发生误诊和漏诊。据我们所知,尚无MPM并发酒精性肝硬化的病例报道。

病例摘要

一名63岁男性因腹胀20天就诊于我院。他有近30年的饮酒史,无特殊药物使用史或毒物接触史。在社区医院接受酒精性肝硬化治疗后,其症状未明显改善。该患者接受了剖腹探查术和手术切除。病理检查显示为上皮样MPM。术后他接受了化疗和腹腔热灌注治疗。目前,他病情稳定,未发生肿瘤复发。

结论

由于MPM起病隐匿,很容易发生误诊和漏诊。因此,在临床实践中需要了解MPM,做出正确诊断,并提供及时有效的治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6472/9294891/61951324beb5/WJCC-10-6716-g001.jpg

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