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基于影像学的小儿骨外尤文肉瘤诊断:一例报告。

Imaging-based diagnosis for extraskeletal Ewing sarcoma in pediatrics: A case report.

作者信息

Chen Zhi-Hui, Guo He-Qing, Chen Jing-Jing, Zhang Ying, Zhao Li

机构信息

Medical Ultrasound, Affiliated Lishui Hospital of Zhejiang University, The Fifth Affiliated Hospital of Wenzhou Medical University, The Central Hospital of Zhejiang Lishui, Lishui 323000, Zhejiang Province, China.

Medical Ultrasound, Women and Children Hospital of Shaoxing, Shaoxing 312000, Zhejiang Province, China.

出版信息

World J Clin Cases. 2022 Jul 6;10(19):6595-6601. doi: 10.12998/wjcc.v10.i19.6595.

Abstract

BACKGROUND

Extraskeletal Ewing sarcoma (EES) is a member of the Ewing sarcoma family of tumors which is pathologically known as a small, round, blue cell tumor involving bone and soft tissue. The prevalence of EES is only 15%-25% of all Ewing sarcoma and EES often occurs in patients aged from 20-mo-old to 30-years-old resulting in an unfavorable prognosis.

CASE SUMMARY

The present case report described a 7-year-old patient with a palpable EES mass of 33 mm × 27 mm × 28 mm in the deep neck with symptoms of persistent dyspnea over the past 5 mo. After laboratory examinations, abnormal physiological and biochemical indicators were not found. Ultrasound images presented the mass to be complex, solid and fluid-filled with circumscribed margins and posterior acoustic enhancement. The mass also presented with partial internal vascularity. The contrast-enhanced magnetic resonance imaging scan illustrated the outstanding enhancement with fast perfusion mode in the early arterial phase.

CONCLUSION

Our study suggested that a quick-growing mass in the pediatric patient is possibly a malignant tumor whether the mass has well-defined margins or not.

摘要

背景

骨外尤文肉瘤(EES)是尤文肉瘤家族肿瘤的一员,在病理学上它是一种累及骨骼和软组织的小圆形蓝细胞肿瘤。EES在所有尤文肉瘤中的患病率仅为15%-25%,且常发生于20个月至30岁的患者中,预后不佳。

病例摘要

本病例报告描述了一名7岁患者,其颈部深处可触及一个大小为33 mm×27 mm×28 mm的EES肿块,在过去5个月中一直有持续性呼吸困难的症状。实验室检查后未发现异常的生理和生化指标。超声图像显示该肿块为复杂的、实性和液性混合的,边界清晰,后方回声增强。肿块内部也有部分血管。对比增强磁共振成像扫描显示在动脉早期快速灌注模式下有明显强化。

结论

我们的研究表明,儿科患者中快速生长的肿块,无论其边界是否清晰,都可能是恶性肿瘤。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9660/9294893/c5111ba2418f/WJCC-10-6595-g001.jpg

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