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II型和III型胫骨平台骨折手术后手术部位感染的危险因素识别

Identification of risk factors for surgical site infection after type II and type III tibial pilon fracture surgery.

作者信息

Hu Hao, Zhang Jian, Xie Xue-Guan, Dai Yan-Kun, Huang Xu

机构信息

Department of Orthopaedics, Huai'an Second People's Hospital, Huai'an 223300, Jiangsu Province, China.

出版信息

World J Clin Cases. 2022 Jul 6;10(19):6399-6405. doi: 10.12998/wjcc.v10.i19.6399.

DOI:10.12998/wjcc.v10.i19.6399
PMID:35979296
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9294882/
Abstract

BACKGROUND

High-energy tibial pilon fractures are complex and severe fractures that are associated with a high risk of infection following open reduction and internal fixation. Infection can negatively impact patient outcomes.

AIM

To compare risk factors for postoperative infection after open reduction and internal fixation for a pilon fracture.

METHODS

Among the 137 patients included, 67 developed a surgical site infection. Demographic, clinical, and surgical factors were compared between the two groups. A binary logistic regression analysis was used to determine the odds ratio (OR) and corresponding 95%CI for significant risk factors for postoperative infection.

RESULTS

The distribution of pathogenic bacteria among the 67 patients who developed a surgical site infection was as follows: Gram-positive, 58.2% ( = 39); Gram-negative, 38.8% ( = 26); and fungal, 2.9% ( = 2). The following factors were associated with postoperative infection ( < 0.05): a Ruedi-Allgower pilon fracture type III (OR = 2.034; 95%CI: 1.109-3.738); a type III surgical incision (OR = 1.840; 95%CI: 1.177-2.877); wound contamination (OR = 2.280; 95%CI: 1.378-3.772); and diabetes as a comorbidity (OR = 3.196; 95%CI: 1.209-8.450).

CONCLUSION

Infection prevention for patients with a Ruedi-Allgower fracture type III, surgical incision type III, wound contamination, and diabetes lowers the postoperative infection risk after surgical management of tibial pilon fractures.

摘要

背景

高能胫骨平台骨折是复杂且严重的骨折,切开复位内固定术后感染风险高。感染会对患者预后产生负面影响。

目的

比较胫骨平台骨折切开复位内固定术后感染的危险因素。

方法

纳入的137例患者中,67例发生手术部位感染。比较两组的人口统计学、临床和手术因素。采用二元逻辑回归分析确定术后感染显著危险因素的比值比(OR)及相应的95%置信区间(CI)。

结果

67例发生手术部位感染患者的病原菌分布如下:革兰阳性菌占58.2%(n = 39);革兰阴性菌占38.8%(n = 26);真菌占2.9%(n = 2)。以下因素与术后感染相关(P < 0.05):Ruedi-Allgower III型胫骨平台骨折(OR = 2.034;95%CI:1.109 - 3.738);III类手术切口(OR = 1.840;95%CI:1.177 - 2.877);伤口污染(OR = 2.280;95%CI:1.378 - 3.772);合并糖尿病(OR = 3.196;95%CI:1.209 - 8.450)。

结论

对Ruedi-Allgower III型骨折、III类手术切口、伤口污染和糖尿病患者进行感染预防,可降低胫骨平台骨折手术治疗后的术后感染风险。

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