Hu Hao, Zhang Jian, Xie Xue-Guan, Dai Yan-Kun, Huang Xu
Department of Orthopaedics, Huai'an Second People's Hospital, Huai'an 223300, Jiangsu Province, China.
World J Clin Cases. 2022 Jul 6;10(19):6399-6405. doi: 10.12998/wjcc.v10.i19.6399.
High-energy tibial pilon fractures are complex and severe fractures that are associated with a high risk of infection following open reduction and internal fixation. Infection can negatively impact patient outcomes.
To compare risk factors for postoperative infection after open reduction and internal fixation for a pilon fracture.
Among the 137 patients included, 67 developed a surgical site infection. Demographic, clinical, and surgical factors were compared between the two groups. A binary logistic regression analysis was used to determine the odds ratio (OR) and corresponding 95%CI for significant risk factors for postoperative infection.
The distribution of pathogenic bacteria among the 67 patients who developed a surgical site infection was as follows: Gram-positive, 58.2% ( = 39); Gram-negative, 38.8% ( = 26); and fungal, 2.9% ( = 2). The following factors were associated with postoperative infection ( < 0.05): a Ruedi-Allgower pilon fracture type III (OR = 2.034; 95%CI: 1.109-3.738); a type III surgical incision (OR = 1.840; 95%CI: 1.177-2.877); wound contamination (OR = 2.280; 95%CI: 1.378-3.772); and diabetes as a comorbidity (OR = 3.196; 95%CI: 1.209-8.450).
Infection prevention for patients with a Ruedi-Allgower fracture type III, surgical incision type III, wound contamination, and diabetes lowers the postoperative infection risk after surgical management of tibial pilon fractures.
高能胫骨平台骨折是复杂且严重的骨折,切开复位内固定术后感染风险高。感染会对患者预后产生负面影响。
比较胫骨平台骨折切开复位内固定术后感染的危险因素。
纳入的137例患者中,67例发生手术部位感染。比较两组的人口统计学、临床和手术因素。采用二元逻辑回归分析确定术后感染显著危险因素的比值比(OR)及相应的95%置信区间(CI)。
67例发生手术部位感染患者的病原菌分布如下:革兰阳性菌占58.2%(n = 39);革兰阴性菌占38.8%(n = 26);真菌占2.9%(n = 2)。以下因素与术后感染相关(P < 0.05):Ruedi-Allgower III型胫骨平台骨折(OR = 2.034;95%CI:1.109 - 3.738);III类手术切口(OR = 1.840;95%CI:1.177 - 2.877);伤口污染(OR = 2.280;95%CI:1.378 - 3.772);合并糖尿病(OR = 3.196;95%CI:1.209 - 8.450)。
对Ruedi-Allgower III型骨折、III类手术切口、伤口污染和糖尿病患者进行感染预防,可降低胫骨平台骨折手术治疗后的术后感染风险。