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新型冠状病毒肺炎相关肺曲霉病的不寻常表现:一例报告

Unusual manifestation of COVID-19-associated pulmonary aspergillosis: A case report.

作者信息

Albaji Maryam, Fattahi Mohammad Reza, Iranmehr Arad

机构信息

Department of Pulmonary Disease Sina Hospital, Tehran University of Medical Sciences Tehran Iran.

Department of Radiology Sina Hospital, Tehran University of Medical Sciences Tehran Iran.

出版信息

Clin Case Rep. 2022 Aug 11;10(8):e6188. doi: 10.1002/ccr3.6188. eCollection 2022 Aug.

DOI:10.1002/ccr3.6188
PMID:35979382
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9366931/
Abstract

A young man, a recent coronavirus patient, was readmitted with hypoesthesia and dysarthria following a rapid deterioration of respiratory symptoms. The brain and lung CT scans revealed ischemia and cavitary lung lesions. Clinical suspicion for aspergillus leads to prompt treatment, confirmed by biopsy. Neurologic and pulmonary symptoms resolved ultimately.

摘要

一名年轻男子,近期的新冠病毒患者,在呼吸道症状迅速恶化后因感觉减退和构音障碍再次入院。脑部和肺部CT扫描显示有缺血和肺部空洞性病变。临床怀疑为曲霉菌感染,遂立即进行治疗,活检结果证实了这一诊断。最终,神经和肺部症状得到缓解。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04af/9366931/e54d23b6fd0c/CCR3-10-e6188-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04af/9366931/781027b702e7/CCR3-10-e6188-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04af/9366931/3cec89ef58d1/CCR3-10-e6188-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04af/9366931/e54d23b6fd0c/CCR3-10-e6188-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04af/9366931/781027b702e7/CCR3-10-e6188-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04af/9366931/3cec89ef58d1/CCR3-10-e6188-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/04af/9366931/e54d23b6fd0c/CCR3-10-e6188-g004.jpg

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本文引用的文献

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Taskforce report on the diagnosis and clinical management of COVID-19 associated pulmonary aspergillosis.新型冠状病毒肺炎相关肺曲霉病诊断与临床管理特别工作组报告
Intensive Care Med. 2021 Aug;47(8):819-834. doi: 10.1007/s00134-021-06449-4. Epub 2021 Jun 23.
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Defining and managing COVID-19-associated pulmonary aspergillosis: the 2020 ECMM/ISHAM consensus criteria for research and clinical guidance.定义和管理新型冠状病毒肺炎相关肺曲霉病:2020年欧洲临床微生物与感染性疾病学会/国际人类与动物真菌学会研究和临床指南共识标准
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Central nervous system aspergillosis in immunocompetent patients: Case series and literature review.
免疫功能正常患者的中枢神经系统曲霉病:病例系列及文献综述
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BMC Pulm Med. 2020 Sep 9;20(1):239. doi: 10.1186/s12890-020-01257-w.
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Epidemiology of Invasive Pulmonary Aspergillosis Among Intubated Patients With COVID-19: A Prospective Study.COVID-19 气管插管患者侵袭性肺曲霉病的流行病学:一项前瞻性研究。
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Confronting and mitigating the risk of COVID-19 associated pulmonary aspergillosis.应对和减轻 COVID-19 相关肺曲霉病的风险。
Eur Respir J. 2020 Oct 1;56(4). doi: 10.1183/13993003.02554-2020. Print 2020 Oct.
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COVID-19-associated invasive pulmonary aspergillosis.新型冠状病毒肺炎相关侵袭性肺曲霉病
Ann Intensive Care. 2020 Jun 1;10(1):71. doi: 10.1186/s13613-020-00686-4.
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Prevalence of putative invasive pulmonary aspergillosis in critically ill patients with COVID-19.新型冠状病毒肺炎(COVID-19)重症患者中疑似侵袭性肺曲霉病的患病率。
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