甲醇作为氢源：α,β-不饱和酮的室温高选择性转移氢化反应
Methanol as a hydrogen source: room-temperature highly-selective transfer hydrogenation of α,β-unsaturated ketones.
作者信息
Garg Nidhi, Somasundharam Hari Prasaad, Dahiya Pardeep, Sundararaju Basker
机构信息
Department of Chemistry, Indian Institute of Technology Kanpur, Kanpur, Uttar Pradesh, 208 016, India.
出版信息
Chem Commun (Camb). 2022 Sep 1;58(71):9930-9933. doi: 10.1039/d2cc03597a.
The described system offers an ideal, user-friendly protocol for the chemoselective homogeneous hydrogenation of α,β-unsaturated ketones at room temperature using methanol as a liquid organic hydrogen carrier. Excellent yields were achieved with an -prepared phosphine-free Cp*Ir(III)/bipyridonate complex. Chemoselective reduction with other reducible functionalities and late-stage functionalization were also explored.
所描述的系统提供了一种理想的、用户友好的方案，用于在室温下使用甲醇作为液体有机氢载体对α,β-不饱和酮进行化学选择性均相氢化。使用一种制备的无膦Cp*Ir(III)/联吡啶酸酯配合物实现了优异的产率。还探索了与其他可还原官能团的化学选择性还原以及后期官能化。
Zotero 插件