针对 mTOR 通路预防 ER 阴性乳腺癌。
Targeting the mTOR Pathway for the Prevention of ER-Negative Breast Cancer.
机构信息
Department of Clinical Cancer Prevention, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Department of Molecular and Cellular Biology, Baylor College of Medicine, Houston, Texas.
出版信息
Cancer Prev Res (Phila). 2022 Dec 1;15(12):791-802. doi: 10.1158/1940-6207.CAPR-22-0106.
Abstract
Our results show that everolimus delays mammary tumor formation in multiple mouse models, suggesting that mTOR inhibitors will be useful for the prevention of ER-negative and triple-negative breast cancer in humans. See related Spotlight, p. 787.
摘要
我们的研究结果表明，依维莫司可延缓多种小鼠模型的乳腺癌形成，这提示 mTOR 抑制剂可能对 ER 阴性和三阴性乳腺癌的预防具有潜在临床应用价值。详见相关专题报道，第 787 页。
Zotero 插件