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Mitochondrial apoptosis: facilitator of NK cell-mediated immunotherapy.

作者信息

Ullrich Evelyn, Vogler Meike, von Metzler Ivana

机构信息

University Hospital Frankfurt, Department for Children and Adolescents Medicine, Goethe University, Frankfurt am Main, Germany.

Experimental Immunology, Goethe University, Frankfurt am Main, Germany.

出版信息

Signal Transduct Target Ther. 2022 Aug 18;7(1):291. doi: 10.1038/s41392-022-01126-4.

Abstract
摘要

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Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis.
Cell. 2022 Apr 28;185(9):1521-1538.e18. doi: 10.1016/j.cell.2022.03.030. Epub 2022 Apr 20.
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Oncoimmunology. 2020 Sep 2;9(1):1777651. doi: 10.1080/2162402X.2020.1777651.
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Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors.
N Engl J Med. 2020 Feb 6;382(6):545-553. doi: 10.1056/NEJMoa1910607.
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NK cells switch from granzyme B to death receptor-mediated cytotoxicity during serial killing.
J Exp Med. 2019 Sep 2;216(9):2113-2127. doi: 10.1084/jem.20181454. Epub 2019 Jul 3.

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