Crema Michel D, Guermazi Ali, Roemer Frank W
Institute of Sports Imaging, Sports Medicine Department, French National Institute of Sports (INSEP), 11 avenue du Tremblay, 75012, Paris, France.
Quantitative Imaging Center, Boston University School of Medicine, Boston, MA, USA.
Skeletal Radiol. 2023 May;52(5):923-931. doi: 10.1007/s00256-022-04150-1. Epub 2022 Aug 18.
Osteoarthritis (OA) is among the most common diseases affecting both axial and appendicular joints and the lead cause of disability worldwide. OA incidence is rising due to extended life expectancy and the increasing obesity epidemic. Several joint interventions are available to manage pain and joint function in patients with OA, most of these treatments being widely applied using intra-articular injections. In this chapter, we will describe the different joint interventions available for the management of pain in OA focusing on intra-articular injections, including discussion on the evidence regarding the efficacy of these treatments, based on the most recent systematic reviews and meta-analyses available. We also discuss the importance of imaging in guiding these treatments, including the different imaging modalities available for intra-articular injection guidance, their advantages, and disadvantages. Finally, we briefly discuss safety data and the consensus regarding the most used intra-articular treatments to manage pain in OA.
骨关节炎（OA）是影响轴关节和附属关节的最常见疾病之一，也是全球致残的主要原因。由于预期寿命延长和肥胖症流行加剧，OA的发病率正在上升。对于OA患者，有几种关节干预措施可用于控制疼痛和关节功能，其中大多数治疗方法通过关节内注射广泛应用。在本章中，我们将描述可用于管理OA疼痛的不同关节干预措施，重点是关节内注射，包括根据现有最新系统评价和荟萃分析，讨论这些治疗方法疗效的证据。我们还讨论了成像在指导这些治疗中的重要性，包括可用于关节内注射指导的不同成像方式、它们的优缺点。最后，我们简要讨论安全性数据以及关于OA疼痛管理中最常用关节内治疗方法的共识。
