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莫旺综合征表现为自身免疫性副肿瘤性脑炎,与胸腺瘤相关,并通过F 18氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描检测到抗电压门控钾通道(富含亮氨酸,胶质瘤失活1)抗体。

Morvan Syndrome Manifesting as Autoimmune Paraneoplastic Encephalitis Associated with Thymoma and Antivoltage Gated Potassium Channel (Leucine Rich, Glioma Inactivated 1) Antibody Detected using F 18 Fluorodeoxyglucose Positron Emission Tomography/Computed Tomography.

作者信息

Kamaleshwaran Koramadai Karuppusamy, Senthilkumar Elumalai, Ramkumar Elumalai, Ruth Rajasekaran

机构信息

Department of Nuclear Medicine, PET/CT and Radionuclide Therapy, Kovai Medical Center and Hospital Limited, Coimbatore, Tamil Nadu, India.

Department of Neurology, Kovai Medical Center and Hospital Limited, Coimbatore, Tamil Nadu, India.

出版信息

Indian J Nucl Med. 2022 Apr-Jun;37(2):166-168. doi: 10.4103/ijnm.ijnm_155_21. Epub 2022 Jul 8.

Abstract

Morvan's syndrome (MoS) is a rare, complex neurological disorder characterized by neuromyotonia, neuropsychiatric features, dysautonomia, and neuropathic pain. The majority of MoS cases have a paraneoplastic etiology, most commonly thymoma, usually occurring before the diagnosis of the underlying tumor and showing improvement following surgery. We present a case of 60-year-old patient presenting with suspicious of MoS and autoimmune encephalitis (AE), F-18 fluorodeoxyglucose positron emission tomography/computed tomography as single imaging modality detected and confirmed both AE and thymoma.

摘要

莫旺综合征(MoS)是一种罕见的复杂性神经疾病,其特征为神经肌强直、神经精神症状、自主神经功能障碍和神经性疼痛。大多数莫旺综合征病例有副肿瘤病因,最常见的是胸腺瘤,通常在潜在肿瘤诊断之前出现,并在手术后有所改善。我们报告一例60岁患者,疑似患有莫旺综合征和自身免疫性脑炎(AE),氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描作为单一成像方式检测并确诊了自身免疫性脑炎和胸腺瘤。

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