Department of Bioscience, Graduate School of Science and Technology, Shizuoka University, Shizuoka, Japan.
Department of Agriculture, Graduate School of Integrated Science and Technology, Shizuoka University, Shizuoka, Japan.
Biosci Biotechnol Biochem. 2022 Sep 23;86(10):1327-1332. doi: 10.1093/bbb/zbac117.
Five compounds including a new compound (1) were isolated from mycelia of a mushroom-forming fungus Agaricus blazei. Compound 2 was isolated from nature for the first time. Their structures were determined by the interpretation of spectroscopic data. In the bioassay examining growth inhibitory activity against phytopathogenic bacteria Clavibacter michiganensis, Burkholderia glumae, and Peptobacterium carotovorum, all the compounds showed inhibition effects on C. michiganensis. Compounds 3 and 4 also showed weak inhibitory activity against growth of B. glumae.
五种化合物,包括一种新化合物(1),从蘑菇形成真菌 Blazei 蘑菇的菌丝体中分离得到。化合物 2 是首次从自然界中分离得到的。通过对光谱数据的解释确定了它们的结构。在检查对植物病原菌 Michiganensis、Burkholderia glumae 和 Peptobacterium carotovorum 生长抑制活性的生物测定中,所有化合物对 C. michiganensis 均表现出抑制作用。化合物 3 和 4 也对 B. glumae 的生长表现出微弱的抑制活性。