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超声心动图在需要左心室辅助装置治疗的患者的选择、植入及管理中的实际作用的最新进展

Update on the Practical Role of Echocardiography in Selection, Implantation, and Management of Patients Requiring Left Ventricular Assist Device Therapy.

作者信息

Katapadi Aashish, Umland Matt, Khandheria Bijoy K

机构信息

Aurora Cardiovascular and Thoracic Services, Aurora Sinai/Aurora St. Luke's Medical Centers, Advocate Aurora Health, 2801 W. Kinnickinnic River Parkway, Ste. 880, Milwaukee, WI, 53215, USA.

School of Medicine and Public Health, University of Wisconsin, Milwaukee, WI, 53215, USA.

出版信息

Curr Cardiol Rep. 2022 Nov;24(11):1587-1597. doi: 10.1007/s11886-022-01771-9. Epub 2022 Aug 19.

DOI:10.1007/s11886-022-01771-9
PMID:35984555
Abstract

PURPOSE OF REVIEW

Echocardiography is a valuable tool for management of patients with a left ventricular assist device (LVAD). We present an updated review on the practical applications of the role of echocardiography for pre- and postoperative evaluation of patients selected.

RECENT FINDINGS

The LVAD is a temporary or permanent option for patients with advanced heart failure who are unresponsive to other therapy. Use of the device has its own risks, and implantation remains a complex procedure. Transthoracic and transesophageal echocardiography are useful tools for patient evaluation and monitoring both peri- and postoperatively, as we previously presented. Assessment of left and right ventricular function, complications such as thrombus formation or intracardiac shunting, and valvular disease are all important in this assessment. This also aids in predicting postoperative complications. Placement of the device is confirmed intraoperatively, and subsequent ramp studies are used to determine optimal device settings. Right ventricular (RV) failure is the most common postoperative complication and preoperative evaluation of its function is crucial. Studies suggest that tricuspid annular plane systolic excursion, RV fractional area change, and RV global longitudinal strain are strong predictors of RV failure; LV ejection fraction, size, and end-diastolic diameter are also important markers. Aortic regurgitation and mitral stenosis must always be corrected prior to LVAD placement. However, direct visualization before and after implantation, especially to rule out potential contraindications such as thrombi, cannot be overemphasized. Ramp studies remain an integral part of device optimization and may result in greater myocardial recovery than previously realized.

摘要

综述目的

超声心动图是管理左心室辅助装置(LVAD)患者的一项重要工具。我们对超声心动图在所选患者术前和术后评估中的实际应用进行了最新综述。

最新发现

对于对其他治疗无反应的晚期心力衰竭患者,LVAD是一种临时或永久性的选择。使用该装置有其自身风险,植入仍是一个复杂的过程。如我们之前所述,经胸和经食管超声心动图是患者围手术期和术后评估及监测的有用工具。评估左、右心室功能、血栓形成或心内分流等并发症以及瓣膜疾病在该评估中均很重要。这也有助于预测术后并发症。术中确认装置的放置,随后进行斜坡试验以确定最佳装置设置。右心室(RV)衰竭是最常见的术后并发症,术前对其功能的评估至关重要。研究表明,三尖瓣环平面收缩期位移、RV面积变化分数和RV整体纵向应变是RV衰竭的有力预测指标;左心室射血分数、大小和舒张末期直径也是重要指标。在植入LVAD之前,必须始终纠正主动脉瓣反流和二尖瓣狭窄。然而,植入前后的直接可视化,尤其是排除血栓等潜在禁忌症,再怎么强调都不为过。斜坡试验仍然是装置优化的一个组成部分,可能会带来比之前认识到的更大的心肌恢复。

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