Krebs-Drouot Lila, Karpathiou Georgia, Scolan Virginie, Bidat-Callet Carolyne, Boyer Baptiste, Péoc'h Michel
Forensic Medicine Department, Grenoble Alpes University Hospital, La Tronche, Grenoble, France.
Pathology Department, University Hospital of Saint-Etienne, Saint-Etienne, France.
Forensic Sci Med Pathol. 2023 Mar;19(1):60-66. doi: 10.1007/s12024-022-00516-y. Epub 2022 Aug 19.
Acute myeloid leukaemia (AML) is a rare haematologic cancer with a rapid increase in blast cells, which need to be rapidly diagnosed and treated. The aim of this report is to analyse the rare phenomenon of AML diagnosed at autopsy after sudden death. We report three cases of AML and perform a literature review using the mesh terms "sudden death" and "leukaemia". We report the cases of three young women diagnosed with AML only after autopsy. We found seven articles which reported sudden death due to AML diagnosed at autopsy. Diagnosis of AML during autopsy is rare but can raise forensic issues. A complete autopsy with pathology analysis is needed.
急性髓系白血病(AML)是一种罕见的血液系统癌症,其原始细胞迅速增加,需要迅速诊断和治疗。本报告的目的是分析猝死后经尸检确诊的AML这一罕见现象。我们报告了3例AML病例,并使用“猝死”和“白血病”等主题词进行了文献综述。我们报告了3名年轻女性仅在尸检后才被诊断为AML的病例。我们发现7篇文章报道了尸检时诊断出的AML导致的猝死。尸检期间诊断出AML很罕见,但可能引发法医问题。需要进行完整的尸检并进行病理分析。