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多腔室动态对比磁共振淋巴造影在复杂性淋巴畸形诊断中的应用

Multicompartment Dynamic Contrast Magnetic Resonance Lymphangiography in Diagnosis of Complicated Lymphatic Anomaly.

机构信息

Comprehensive Vascular Anomalies Program, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

Division of Oncology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

出版信息

Lymphat Res Biol. 2023 Apr;21(2):135-140. doi: 10.1089/lrb.2022.0012. Epub 2022 Aug 17.

Abstract

To describe the dynamic contrast magnetic resonance lymphangiography (DCMRL) findings of three patients with complicated lymphatic anomaly (CLA) and protein losing enteropathy. We further discuss the importance of a multicompartment (intrahepatic [IH], intramesenteric [IM], and intranodal [IN]) DCMRL in delineating central lymphatic flow pathologies. This is a retrospective study of three patients-one adult and two children who individually underwent the three-compartment DCMRL, namely IN-DCMRL, IH-DCMRL, and IM-DCMCRL. Findings from the results of the DCMRL for these three patients were obtained from the medical records and compared. Using the multicompartment imaging modalities, chylous fluid leakage into the peritoneum was observed using IM-DCMRL and IH-DCMRL but not IN-DCMRL for one of the patients in the case series. In contrast, leakage of chyle into the mediastinum was noted using IN-DCMRL but not IH-DCMRL and IM-DCMRL on another patient in this case series. Owing to the variability in outlining lymphatic flow pathologies, multicompartment imaging gives a more global picture of individual conduction disorders, has the potential to improve clinical assessment, and in some cases leads to a diagnosis of the abnormality and thus provides a better understanding of lymphatic flow anomalies in patients with CLAs.

摘要

描述三例伴有复杂淋巴异常(CLA)和蛋白丢失性肠病的患者的动态对比磁共振淋巴造影(DCMRL)表现。我们进一步讨论了多腔室(肝内[IH]、肠系膜内[IM]和淋巴结内[IN])DCMRL 在描绘中央淋巴流病理方面的重要性。本研究回顾性分析了三例患者(1 例成人和 2 例儿童),他们分别进行了三腔室 DCMRL,即 IN-DCMRL、IH-DCMRL 和 IM-DCMCRL。从这三例患者的 DCMRL 结果中获得了这些患者的医疗记录并进行了比较。使用多腔室成像方式,肠系膜内 DCMRL 和 IH-DCMRL 观察到一例患者的乳糜液漏入腹腔,但 IN-DCMRL 则没有。相比之下,在本病例系列中的另一位患者中,使用 IN-DCMRL 观察到乳糜液漏入纵隔,但 IH-DCMRL 和 IM-DCMRL 则没有。由于淋巴流病理的可变性,多腔室成像提供了个体传导障碍的更全面的图像,有可能改善临床评估,并且在某些情况下可以诊断异常,从而更好地了解 CLA 患者的淋巴流异常。

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