Piepmeier J M
J Neurosurg. 1987 Aug;67(2):177-81. doi: 10.3171/jns.1987.67.2.0177.
The records of 60 patients with low-grade astrocytic tumors of the cerebral hemispheres treated between 1975 and 1985 were examined to evaluate the results of current treatment methods. This analysis revealed that the patient's age and tumor enhancement on computerized tomography (CT) with intravenous administration of contrast material were the only factors that influenced survival time. Compared to prior studies, the patients in this report more frequently had normal preoperative neurological examinations and total resection of their lesions. These differences may have resulted from the use of CT scans over the past decade. Earlier diagnosis and improvement definition of the tumor location and extent are two reasons why the use of CT scans may have affected outcome statistics. A re-examination of treatment methods and the timing of those treatments is needed to define the optimal management of these lesions.
对1975年至1985年间接受治疗的60例大脑半球低级别星形细胞瘤患者的记录进行了检查,以评估当前治疗方法的效果。该分析显示,患者的年龄以及静脉注射造影剂后计算机断层扫描(CT)上肿瘤的强化情况是影响生存时间的唯一因素。与先前的研究相比,本报告中的患者术前神经学检查更常正常,且病变全切除。这些差异可能是过去十年使用CT扫描所致。早期诊断以及肿瘤位置和范围定义的改善是使用CT扫描可能影响结果统计的两个原因。需要重新审视治疗方法及其治疗时机,以确定这些病变的最佳管理方案。