Tsai A C, Gong T W
J Nutr. 1987 Jun;117(6):1149-53. doi: 10.1093/jn/117.6.1149.
An experiment was conducted to determine the effects and interactions of exercise-retirement and dietary fat intake on body composition and hepatic lipogenic enzyme activities in hamsters. Forty-eight adult female hamsters were randomly allotted to eight groups of six each for a 40-d experiment. Exercise was in the form of voluntary wheel-running. Four groups served as either exercise or sedentary controls and were fed either a low or a high fat diet for 40 d, in a factorial fashion. Another four groups had access to exercise for 32 d and were then retired for 8 d. Of these four groups, two were fed either the low or high fat diet for the entire 40-d period; the other two were changed to the other diet on d 32. Results showed that compared to sedentary hamsters, exercise hamsters had greater body weight gain but less body fat content and hepatic lipogenic enzyme activities. Under both sedentary and exercise conditions, high fat-fed hamsters had lower hepatic lipogenic enzyme activities and less body fat content than low fat-fed hamsters. Upon retirement, high fat feeding led to a faster increase in body fat especially in previously high fat-fed hamsters. Results of this study suggest that dietary fat intake can significantly modulate the exercise and retirement effects with respect to body weight gain and body fat content.
进行了一项实验，以确定运动-退休和膳食脂肪摄入对仓鼠身体组成和肝脏脂肪生成酶活性的影响及相互作用。48只成年雌性仓鼠被随机分成8组，每组6只，进行为期40天的实验。运动形式为自愿轮转跑步。4组作为运动组或久坐对照组，以析因设计的方式分别喂食低脂或高脂饮食40天。另外4组有32天的运动时间，然后退休8天。在这4组中，2组在整个40天期间喂食低脂或高脂饮食；另外2组在第32天改为另一种饮食。结果表明，与久坐的仓鼠相比，运动的仓鼠体重增加更多，但体脂含量和肝脏脂肪生成酶活性更低。在久坐和运动条件下，高脂喂养的仓鼠肝脏脂肪生成酶活性和体脂含量均低于低脂喂养的仓鼠。退休后，高脂喂养导致体脂增加更快，尤其是之前高脂喂养的仓鼠。本研究结果表明，膳食脂肪摄入可显著调节运动和退休对体重增加和体脂含量的影响。
