Tsai A C, Bach J, Borer K T
Am J Clin Nutr. 1981 Mar;34(3):373-6. doi: 10.1093/ajcn/34.3.373.
Effects of abrupt discontinuation of chronic exercise on body composition and serum lipid, insulin, and glucagon concentrations were examined in adult female hamsters. Thirty-six hamsters (100 to 120 g) were randomly allotted to two groups of 18 each for an 84-day study. One group served as controls and were sedentary throughout the experimental period; another group had access to voluntary running on horizontal discs during the first 42 days of the experimental period. Six hamsters from each group were killed at the end of the exercise period and at 12 and 42 days after retirement. Results showed that hamsters engaged in high levels of voluntary activity increased food intake by about 10 to 20% and this effect persisted for about 10 days after retirement. Voluntary running resulted in a 60% reduction in body fat content and a 30% decrease in serum triglyceride levels. Exercise was also associated with an increase in body cholesterol level, a decrease in glucagon concentration, and a suggestive increase in serum insulin level. Increased food consumption and changes in serum insulin and glucagon may reflect compensatory adjustments to increased energy expenditure of exercise. Discontinuation of exercise resulted in a reversal of exercise effects on body fat, body cholesterol, and serum triglyceride levels.
在成年雌性仓鼠中研究了长期运动突然停止对身体成分以及血清脂质、胰岛素和胰高血糖素浓度的影响。36只仓鼠（100至120克）被随机分为两组，每组18只，进行为期84天的研究。一组作为对照组，在整个实验期间 sedentary；另一组在实验期的前42天可以在水平圆盘上自愿跑步。每组6只仓鼠在运动期结束时以及停止运动后12天和42天被处死。结果显示，进行高水平自愿活动的仓鼠食物摄入量增加了约10%至20%，且这种影响在停止运动后持续约10天。自愿跑步使体脂含量降低了60%，血清甘油三酯水平降低了30%。运动还与身体胆固醇水平升高、胰高血糖素浓度降低以及血清胰岛素水平有提示性升高有关。食物消耗增加以及血清胰岛素和胰高血糖素的变化可能反映了对运动增加的能量消耗的代偿性调整。停止运动导致运动对体脂、身体胆固醇和血清甘油三酯水平的影响发生逆转。
