Ural Federal University, Yekaterinburg, Russia.
Ural Federal University, Yekaterinburg, Russia.
Prog Biophys Mol Biol. 2022 Nov;175:3-13. doi: 10.1016/j.pbiomolbio.2022.08.003. Epub 2022 Aug 17.
A review of the physicochemical models of the movement of protocells and bacteria was performed. The mechanisms of gliding and movement based on flagella are considered. Based on the models, the average speed of movement of protocells and bacteria was calculated. A physicochemical model of bacterial gliding was constructed. The efficiency of the process of converting the energy of ATP into the energy of motion is estimated. A review of models of movement with the help of flagella was performed. A model has been constructed for converting ATP energy into proton and sodium motive forces, which, in turn, are converted into energy of rotor rotation. The problem of the accuracy of operation of nanomachines, on the basis of which the directed movement of bacteria occurs, is discussed. The considered models can be applied to create nanomotors for medical purposes.
对原核细胞和细菌运动的物理化学模型进行了综述。考虑了基于鞭毛的滑行和运动机制。基于这些模型，计算了原核细胞和细菌的平均运动速度。构建了细菌滑行的物理化学模型。估计了将 ATP 能量转化为运动能量的过程的效率。利用鞭毛进行运动的模型进行了回顾。构建了一个将 ATP 能量转化为质子和钠离子动力的模型，质子和钠离子动力继而转化为转子旋转的能量。讨论了基于定向细菌运动发生的纳米机器操作精度的问题。所考虑的模型可用于创建用于医疗目的的纳米马达。
