目前西班牙青少年及青年成人（AYA）肉瘤患者治疗情况调查结果。

Results of a survey on the treatment of adolescents and young adult (AYA) sarcoma patients in Spain at present time.

机构信息

Hospital Universitario Materno Infantil Gregorio Marañón. Pediatric and Adolescent Oncohematology Unit, Madrid, Spain.

Hospital Universitario Virgen del Rocío, Sevilla, Spain.

出版信息

Clin Transl Oncol. 2022 Dec;24(12):2475-2479. doi: 10.1007/s12094-022-02912-w. Epub 2022 Aug 21.

DOI:10.1007/s12094-022-02912-w

PMID:35988093

Abstract

INTRODUCTION

We aimed to analyse health care services for adolescents and young adults (AYA) with sarcomas in Spain.

METHODS

A survey was sent to all Spanish cancer centres, including questions about demographic, facilities, and treatment strategies for AYAs with sarcomas in the last 2 years.

RESULTS

Thirty-five units participated in the survey, 17 paediatric and 15 adult units. There were three specialized AYA units. First line regimen varied depending on whether the treating unit was paediatric or not, for osteosarcomas, rhabdomyosarcomas, and non-rhabdomyosarcomas. By contrast, 91.4% of Ewing sarcomas were treated according to EE2012. In the relapse setting, differences between units were higher in all tumours. Additionally, 48% of the units reported not having trials for this population.

CONCLUSION

There are major differences in the treatment of AYAs with sarcomas between adult and paediatric units. Enormous efforts are needed to homogenize treatments and increase the access to innovation.

摘要

简介

本研究旨在分析西班牙青少年和年轻成人（AYA）肉瘤患者的医疗服务。

方法

向所有西班牙癌症中心发送了一项调查，其中包括过去 2 年中针对 AYA 肉瘤患者的人口统计学、设施和治疗策略相关问题。

结果

35 个单位参与了调查，其中 17 个为儿科单位，15 个为成人单位。有三个专门的 AYA 单位。一线治疗方案取决于治疗单位是儿科还是成人单位，骨肉瘤、横纹肌肉瘤和非横纹肌肉瘤的方案不同。相比之下，91.4%的尤文肉瘤患者按照 EE2012 进行治疗。在复发情况下，所有肿瘤的单位之间差异更大。此外，48%的单位报告没有针对该人群的试验。