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大再生性结节和局灶性结节样增生样病变:定义、发病机制和影像学表现。

Large Regenerative Nodules and Focal Nodular Hyperplasia-Like Lesions: Definition, Pathogenesis, and Imaging Findings.

机构信息

Department of Radiology, Northwestern University Feinberg School of Medicine, 676 North Saint Claire Street, Arkes Family Pavillion, Suite 800, Chicago, IL 60611, USA.

Department of Radiology, Northwestern University Feinberg School of Medicine, 676 North Saint Claire Street, Arkes Family Pavillion, Suite 800, Chicago, IL 60611, USA.

出版信息

Radiol Clin North Am. 2022 Sep;60(5):795-808. doi: 10.1016/j.rcl.2022.05.004. Epub 2022 Jul 8.

DOI:10.1016/j.rcl.2022.05.004
PMID:35989045
Abstract

Focal nodular hyperplasia-like (FNH-like) nodules are hepatocellular lesions with similar radiologic and pathologic features as typical FNH but occur within an abnormal liver. They arise due to alteration of hepatic vasculature at both the microscopic and macroscopic levels. Although these nodules are not thought to have malignant potential, their imaging features overlap with premalignant and malignant lesions including hepatocellular carcinoma (HCC) and arise in patients who may be at risk for HCC, posing a diagnostic and management dilemma. It is important to consider these benign entities when reviewing liver imaging of patients at risk for HCC to reduce unnecessary interventions.

摘要

局灶性结节样增生样(FNH-样)结节是一种具有与典型 FNH 相似的影像学和病理学特征的肝细胞病变,但发生在异常肝脏内。它们是由于肝血管在微观和宏观水平上的改变而产生的。尽管这些结节不被认为具有恶性潜能,但它们的影像学特征与包括肝细胞癌(HCC)在内的癌前和恶性病变重叠,并发生在可能有 HCC 风险的患者中,这给诊断和管理带来了困境。在对有 HCC 风险的患者的肝脏影像学进行评估时,考虑这些良性病变对于减少不必要的干预非常重要。

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