Baginski Bryana N, Byrne Kaileigh A, Demosthenes Lauren, Roth Prerana J
University of South Carolina School of Medicine Greenville, Greenville, SC, USA.
Department of Psychology, Clemson University, Clemson, SC, USA.
Subst Abuse. 2022 Aug 12;16:11782218221115583. doi: 10.1177/11782218221115583. eCollection 2022.
Comorbidities between Substance Use Disorder (SUD) and mental health disorders are highly prevalent, yet there remains a lack of information regarding how mental health conditions may affect addiction severity. Consequently, this study sought to investigate the relationship between internalizing disorders (anxiety and mood disorders) and addiction severity in patients hospitalized for SUD-related medical complications. Individual difference predictors and history of prior treatment for SUD were also examined.
Participants (N = 200) were hospitalized patients who consented to receive peer-based recovery support services for their SUD. To be eligible for the study, participants needed to have a SUD diagnosis due to alcohol, opioids, methamphetamine, cocaine, or a combination of these substances (polysubstance use). Participants completed self-report questionnaires regarding demographics, mental health history, prior SUD treatment, and addiction severity (Drug and Alcohol Screening Test; DAST-10) during their hospitalization.
Results showed that patients with Generalized Anxiety Disorder (GAD) ( = 6.68, SD = 2.97) had greater addiction severity compared to those without GAD ( = 5.41, SD = 3.34), = .016. Addiction severity results stratified by SUD type showed that the relationship was significant among patients with Alcohol Use Disorder ( = .014), but not among those with other SUD types (s > .27). Major Depressive Disorder (MDD) and Post-Traumatic Stress Disorder (PTSD) were not linked to addiction severity. Among those with GAD, 81.4% had previously been to treatment compared to only 53.1% of those without GAD, = .010. The only participant characteristic linked with addiction severity was insurance status.
GAD may represent a risk factor for advanced alcohol addiction trajectories, including greater addiction severity and severe health complications requiring inpatient hospitalization.
物质使用障碍（SUD）与精神健康障碍的共病现象极为普遍，但关于精神健康状况如何影响成瘾严重程度的信息仍然匮乏。因此，本研究旨在调查因SUD相关医疗并发症住院的患者中内化性障碍（焦虑和情绪障碍）与成瘾严重程度之间的关系。还研究了个体差异预测因素和SUD既往治疗史。
参与者（N = 200）为同意接受基于同伴的SUD康复支持服务的住院患者。为符合研究条件，参与者需因酒精、阿片类药物、甲基苯丙胺、可卡因或这些物质的组合（多物质使用）而被诊断为SUD。参与者在住院期间完成了关于人口统计学、精神健康史、既往SUD治疗和成瘾严重程度（药物和酒精筛查测试；DAST - 10）的自我报告问卷。
结果显示，患有广泛性焦虑症（GAD）的患者（= 6.68，标准差 = 2.97）与未患GAD的患者（= 5.41，标准差 = 3.34）相比，成瘾严重程度更高，= 0.016。按SUD类型分层的成瘾严重程度结果显示，这种关系在酒精使用障碍患者中具有统计学意义（= 0.014），但在其他SUD类型患者中不具有统计学意义（s > 0.27）。重度抑郁症（MDD）和创伤后应激障碍（PTSD）与成瘾严重程度无关。在患有GAD的患者中，81.4%曾接受过治疗，而未患GAD的患者中这一比例仅为53.1%，= 0.010。与成瘾严重程度相关的唯一参与者特征是保险状况。
GAD可能是严重酒精成瘾轨迹的一个风险因素，包括更高的成瘾严重程度和需要住院治疗的严重健康并发症。
