Liang Shuli, Fan Xing, Chen Feng, Liu Yonghong, Qiu Binghui, Zhang Kai, Qi Songtao, Zhang Guojun, Liu Jinfang, Zhang Jianguo, Wang Jun, Wang Xiu, Song Ziyang, Luan Guoming, Yang Xuejun, Jiang Rongcai, Zhang Hua, Wang Lei, You Yongping, Shu Kai, Lu Xiaojie, Gao Guoyi, Zhang Bo, Zhou Jian, Jin Hai, Han Kaiwei, Li Yiming, Wei Junji, Yang Kun, You Gan, Ji Hongming, Jiang Yuwu, Wang Yi, Lin Zhiguo, Li Yan, Liu Xuewu, Hu Jie, Zhu Junming, Li Wenling, Wang Yongxin, Kang Dezhi, Feng Hua, Liu Tinghong, Chen Xin, Pan Yawen, Liu Zhixiong, Li Gang, Li Yunqian, Ge Ming, Fu Xianming, Wang Yuping, Zhou Dong, Li Shichuo, Jiang Tao, Hou Lijun, Hong Zhen
Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, No. 56 Nanlishi Road, Xicheng District, Beijing 100045, China.
Beijing Neurosurgical Institute, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.
Ther Adv Neurol Disord. 2022 Aug 16;15:17562864221114357. doi: 10.1177/17562864221114357. eCollection 2022.
Seizures are a common symptom of craniocerebral diseases, and epilepsy is one of the comorbidities of craniocerebral diseases. However, how to rationally use anti-seizure medications (ASMs) in the perioperative period of craniocerebral surgery to control or avoid seizures and reduce their associated harm is a problem. The China Association Against Epilepsy (CAAE) united with the Trauma Group of the Chinese Neurosurgery Society, Glioma Professional Committee of the Chinese Anti-Cancer Association, Neuro-Oncology Branch of the Chinese Neuroscience Society, and Neurotraumatic Group of Chinese Trauma Society, and selected experts for consultancy regarding outcomes from evidence-based medicine in domestic and foreign literature. These experts referred to the existing research evidence, drug characteristics, Chinese FDA-approved indications, and expert experience, and finished the current guideline on the application of ASMs during the perioperative period of craniocerebral surgery, aiming to guide relevant clinical practice. This guideline consists of six sections: application scope of guideline, concepts of craniocerebral surgery-related seizures and epilepsy, postoperative application of ASMs in patients without seizures before surgery, application of ASMs in patients with seizures associated with lesions before surgery, emergency treatment of postoperative seizures, and 16 recommendations.
癫痫发作是颅脑疾病的常见症状，而癫痫是颅脑疾病的合并症之一。然而，在颅脑手术围手术期如何合理使用抗癫痫药物（ASMs）来控制或避免癫痫发作并减少其相关危害是一个问题。中国抗癫痫协会（CAAE）联合中华医学会神经外科学分会创伤学组、中国抗癌协会神经胶质瘤专业委员会、中国神经科学学会神经肿瘤分会以及中华创伤学会神经创伤学组，挑选专家就国内外文献中循证医学的结果进行咨询。这些专家参考了现有的研究证据、药物特性、中国食品药品监督管理总局批准的适应证以及专家经验，完成了当前关于颅脑手术围手术期ASMs应用的指南，旨在指导相关临床实践。本指南共包括六个部分：指南适用范围、颅脑手术相关癫痫发作和癫痫的概念、术前无癫痫发作患者术后ASMs的应用、术前有与病变相关癫痫发作患者ASMs的应用、术后癫痫发作的紧急处理以及16条推荐意见。
Zotero 插件