Department of Pediatric Neurology, the Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Int J Dev Neurosci. 2022 Oct;82(6):548-553. doi: 10.1002/jdn.10225. Epub 2022 Aug 28.
Guillain-Barré syndrome (GBS) is an immune-mediated polyradiculoneuropathy with the classic presentation of acute onset neurological symptoms preceded by an infective illness, followed by progressive limb weakness. Unilateral facial paralysis is rarely seen in GBS.
We reported a child presented with unilateral facial paralysis, limited outward movement of one eye and unilateral lower limb weakness, who was later diagnosed to have GBS. Through reviewing the patients with similar presentation reported previously, we found that the onset time of unilateral facial weakness in relation to other presentations of GBS seemed to be variable, which could be later or earlier than other symptoms, or concomitant. Most of the patients had a relatively good outcome within 2 weeks to 12 months of follow-up.
Unilateral facial paralysis may be a feature of GBS, albeit a rare thing. Recognising the clinical patterns of such atypical variants of GBS allows for more timely and accurate diagnosis, and for treatment to be initiated without delay.
吉兰-巴雷综合征（GBS）是一种免疫介导的多发神经根神经病，其典型表现为急性发作的神经系统症状，之前有感染性疾病，随后出现进行性肢体无力。GBS 很少出现单侧面瘫。
我们报告了一例以单侧面瘫、一眼外展受限和单侧下肢无力为表现的患儿，后来被诊断为 GBS。通过回顾之前报道的具有类似表现的患者，我们发现单侧面瘫与 GBS 其他表现的发病时间似乎有所不同，可能晚于或早于其他症状，或同时出现。大多数患者在随访 2 周至 12 个月内预后较好。
单侧面瘫可能是 GBS 的一个特征，尽管这种情况较为罕见。认识到 GBS 这种非典型变异的临床模式可以实现更及时、更准确的诊断，并可以立即开始治疗。
