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直接作用抗病毒治疗时代,丙型肝炎病毒感染与未感染的已故供体肾移植受者的 5 年移植物存活率。

Five-Year Allograft Survival for Recipients of Kidney Transplants From Hepatitis C Virus Infected vs Uninfected Deceased Donors in the Direct-Acting Antiviral Therapy Era.

机构信息

Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.

Department of Surgery, Hospital of the University of Pennsylvania, Philadelphia.

出版信息

JAMA. 2022 Sep 20;328(11):1102-1104. doi: 10.1001/jama.2022.12868.

Abstract

This cohort study examines the validity of the Kidney Donor Profile Index’s hepatitis C virus (HCV) penalty during the direct-acting antiviral era by comparing 5-year allograft survival between recipients of kidneys from HCV-RNA–positive donors vs HCV-RNA–negative donors.

摘要

本队列研究通过比较 HCV RNA 阳性供体与 HCV RNA 阴性供体的肾脏受者 5 年移植物存活率,考察了直接作用抗病毒时代下 Kidney Donor Profile Index 的丙型肝炎病毒 (HCV) 处罚的有效性。

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